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Toxin B is essential for virulence of Clostridium difficile.
Lyras D, O'Connor JR, Howarth PM, Sambol SP, Carter GP, Phumoonna T, Poon R, Adams V, Vedantam G, Johnson S, Gerding DN, Rood JI. Lyras D, et al. Among authors: howarth pm. Nature. 2009 Apr 30;458(7242):1176-9. doi: 10.1038/nature07822. Epub 2009 Mar 1. Nature. 2009. PMID: 19252482 Free PMC article.
Methods for gene cloning and targeted mutagenesis.
Carter GP, Lyras D, Poon R, Howarth PM, Rood JI. Carter GP, et al. Among authors: howarth pm. Methods Mol Biol. 2010;646:183-201. doi: 10.1007/978-1-60327-365-7_12. Methods Mol Biol. 2010. PMID: 20597010
TcsL is an essential virulence factor in Clostridium sordellii ATCC 9714.
Carter GP, Awad MM, Hao Y, Thelen T, Bergin IL, Howarth PM, Seemann T, Rood JI, Aronoff DM, Lyras D. Carter GP, et al. Among authors: howarth pm. Infect Immun. 2011 Mar;79(3):1025-32. doi: 10.1128/IAI.00968-10. Epub 2011 Jan 3. Infect Immun. 2011. PMID: 21199912 Free PMC article.
Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections.
Carter GP, Chakravorty A, Pham Nguyen TA, Mileto S, Schreiber F, Li L, Howarth P, Clare S, Cunningham B, Sambol SP, Cheknis A, Figueroa I, Johnson S, Gerding D, Rood JI, Dougan G, Lawley TD, Lyras D. Carter GP, et al. mBio. 2015 Jun 2;6(3):e00551. doi: 10.1128/mBio.00551-15. mBio. 2015. PMID: 26037121 Free PMC article.
11 results