Chen CS - Search Results

1

2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase.

Porchia LM, Guerra M, Wang YC, Zhang Y, Espinosa AV, Shinohara M, Kulp SK, Kirschner LS, Saji M, Chen CS, Ringel MD. Porchia LM, et al. Among authors: chen cs. Mol Pharmacol. 2007 Nov;72(5):1124-31. doi: 10.1124/mol.107.037556. Epub 2007 Aug 2. Mol Pharmacol. 2007. PMID: 17673571

2

Growth inhibitory effects of celecoxib in human umbilical vein endothelial cells are mediated through G1 arrest via multiple signaling mechanisms.

Lin HP, Kulp SK, Tseng PH, Yang YT, Yang CC, Chen CS, Chen CS. Lin HP, et al. Among authors: chen cs. Mol Cancer Ther. 2004 Dec;3(12):1671-80. Mol Cancer Ther. 2004. PMID: 15634661

3

Peroxisome proliferator-activated receptor gamma-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells.

Huang JW, Shiau CW, Yang YT, Kulp SK, Chen KF, Brueggemeier RW, Shapiro CL, Chen CS. Huang JW, et al. Among authors: chen cs, chen kf. Mol Pharmacol. 2005 Apr;67(4):1342-8. doi: 10.1124/mol.104.007732. Epub 2005 Jan 13. Mol Pharmacol. 2005. PMID: 15653552

4

Sensitizing estrogen receptor-negative breast cancer cells to tamoxifen with OSU-03012, a novel celecoxib-derived phosphoinositide-dependent protein kinase-1/Akt signaling inhibitor.

Weng SC, Kashida Y, Kulp SK, Wang D, Brueggemeier RW, Shapiro CL, Chen CS. Weng SC, et al. Among authors: chen cs. Mol Cancer Ther. 2008 Apr;7(4):800-8. doi: 10.1158/1535-7163.MCT-07-0434. Mol Cancer Ther. 2008. Retraction in: Mol Cancer Ther. 2019 Apr;18(4):869. doi: 10.1158/1535-7163.MCT-19-0151. PMID: 18413793 Retracted.

5

Thiazolidinediones mimic glucose starvation in facilitating Sp1 degradation through the up-regulation of beta-transducin repeat-containing protein.

Wei S, Chuang HC, Tsai WC, Yang HC, Ho SR, Paterson AJ, Kulp SK, Chen CS. Wei S, et al. Among authors: chen cs. Mol Pharmacol. 2009 Jul;76(1):47-57. doi: 10.1124/mol.109.055376. Epub 2009 Apr 16. Mol Pharmacol. 2009. PMID: 19372209 Free PMC article.

6

Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma.

Omar HA, Sargeant AM, Weng JR, Wang D, Kulp SK, Patel T, Chen CS. Omar HA, et al. Among authors: chen cs. Mol Pharmacol. 2009 Nov;76(5):957-68. doi: 10.1124/mol.109.058180. Epub 2009 Aug 25. Mol Pharmacol. 2009. PMID: 19706731 Free PMC article.

7

Development of p21 activated kinase-targeted multikinase inhibitors that inhibit thyroid cancer cell migration.

Ma Y, McCarty SK, Kapuriya NP, Brendel VJ, Wang C, Zhang X, Jarjoura D, Saji M, Chen CS, Ringel MD. Ma Y, et al. Among authors: chen cs. J Clin Endocrinol Metab. 2013 Aug;98(8):E1314-22. doi: 10.1210/jc.2012-3937. Epub 2013 May 24. J Clin Endocrinol Metab. 2013. PMID: 23709653 Free PMC article.

8

3-phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells.

Kulp SK, Yang YT, Hung CC, Chen KF, Lai JP, Tseng PH, Fowble JW, Ward PJ, Chen CS. Kulp SK, et al. Among authors: chen cs, chen kf. Cancer Res. 2004 Feb 15;64(4):1444-51. doi: 10.1158/0008-5472.can-03-2396. Cancer Res. 2004. PMID: 14973075

9

From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors.

Zhu J, Huang JW, Tseng PH, Yang YT, Fowble J, Shiau CW, Shaw YJ, Kulp SK, Chen CS. Zhu J, et al. Among authors: chen cs. Cancer Res. 2004 Jun 15;64(12):4309-18. doi: 10.1158/0008-5472.CAN-03-4063. Cancer Res. 2004. PMID: 15205346

10

Overcoming trastuzumab resistance in HER2-overexpressing breast cancer cells by using a novel celecoxib-derived phosphoinositide-dependent kinase-1 inhibitor.

Tseng PH, Wang YC, Weng SC, Weng JR, Chen CS, Brueggemeier RW, Shapiro CL, Chen CY, Dunn SE, Pollak M, Chen CS. Tseng PH, et al. Among authors: chen cs, chen cy. Mol Pharmacol. 2006 Nov;70(5):1534-41. doi: 10.1124/mol.106.023911. Epub 2006 Aug 3. Mol Pharmacol. 2006. PMID: 16887935

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