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Fluorine-containing 6,7-dialkoxybiaryl-based inhibitors for phosphodiesterase 10 A: synthesis and in vitro evaluation of inhibitory potency, selectivity, and metabolism.
Schwan G, Barbar Asskar G, Höfgen N, Kubicova L, Funke U, Egerland U, Zahn M, Nieber K, Scheunemann M, Sträter N, Brust P, Briel D. Schwan G, et al. Among authors: funke u. ChemMedChem. 2014 Jul;9(7):1476-87. doi: 10.1002/cmdc.201300522. Epub 2014 Apr 11. ChemMedChem. 2014. PMID: 24729456
Use of 3-[(18)F]fluoropropanesulfonyl chloride as a prosthetic agent for the radiolabelling of amines: Investigation of precursor molecules, labelling conditions and enzymatic stability of the corresponding sulfonamides.
Löser R, Fischer S, Hiller A, Köckerling M, Funke U, Maisonial A, Brust P, Steinbach J. Löser R, et al. Among authors: funke u. Beilstein J Org Chem. 2013 May 27;9:1002-11. doi: 10.3762/bjoc.9.115. Print 2013. Beilstein J Org Chem. 2013. PMID: 23766817 Free PMC article.
Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.
Villa A, Klein B, Janssen B, Pedragosa J, Pepe G, Zinnhardt B, Vugts DJ, Gelosa P, Sironi L, Beaino W, Damont A, Dollé F, Jego B, Winkeler A, Ory D, Solin O, Vercouillie J, Funke U, Laner-Plamberger S, Blomster LV, Christophersen P, Vegeto E, Aigner L, Jacobs A, Planas AM, Maggi A, Windhorst AD. Villa A, et al. Among authors: funke u. Theranostics. 2018 Oct 27;8(19):5400-5418. doi: 10.7150/thno.25572. eCollection 2018. Theranostics. 2018. PMID: 30555554 Free PMC article.
Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation.
Janssen B, Vugts DJ, Wilkinson SM, Ory D, Chalon S, Hoozemans JJM, Schuit RC, Beaino W, Kooijman EJM, van den Hoek J, Chishty M, Doméné A, Van der Perren A, Villa A, Maggi A, Molenaar GT, Funke U, Shevchenko RV, Baekelandt V, Bormans G, Lammertsma AA, Kassiou M, Windhorst AD. Janssen B, et al. Among authors: funke u. Sci Rep. 2018 Apr 26;8(1):6580. doi: 10.1038/s41598-018-24814-0. Sci Rep. 2018. PMID: 29700413 Free PMC article.
39 results