Giffin M - Search Results

1

Conformational flexibility in the flap domains of ligand-free HIV protease.

Heaslet H, Rosenfeld R, Giffin M, Lin YC, Tam K, Torbett BE, Elder JH, McRee DE, Stout CD. Heaslet H, et al. Among authors: giffin m. Acta Crystallogr D Biol Crystallogr. 2007 Aug;63(Pt 8):866-75. doi: 10.1107/S0907444907029125. Epub 2007 Jul 17. Acta Crystallogr D Biol Crystallogr. 2007. PMID: 17642513

2

A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant.

Giffin MJ, Heaslet H, Brik A, Lin YC, Cauvi G, Wong CH, McRee DE, Elder JH, Stout CD, Torbett BE. Giffin MJ, et al. J Med Chem. 2008 Oct 23;51(20):6263-70. doi: 10.1021/jm800149m. Epub 2008 Sep 30. J Med Chem. 2008. PMID: 18823110 Free PMC article.

3

Identification of broad-based HIV-1 protease inhibitors from combinatorial libraries.

Chang MW, Giffin MJ, Muller R, Savage J, Lin YC, Hong S, Jin W, Whitby LR, Elder JH, Boger DL, Torbett BE. Chang MW, et al. Biochem J. 2010 Aug 1;429(3):527-32. doi: 10.1042/BJ20091645. Biochem J. 2010. PMID: 20507280 Free PMC article.

4

Structure of NFAT1 bound as a dimer to the HIV-1 LTR kappa B element.

Giffin MJ, Stroud JC, Bates DL, von Koenig KD, Hardin J, Chen L. Giffin MJ, et al. Nat Struct Biol. 2003 Oct;10(10):800-6. doi: 10.1038/nsb981. Epub 2003 Aug 31. Nat Struct Biol. 2003. PMID: 12949493

5

Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element.

Bates DL, Barthel KK, Wu Y, Kalhor R, Stroud JC, Giffin MJ, Chen L. Bates DL, et al. Structure. 2008 May;16(5):684-94. doi: 10.1016/j.str.2008.01.020. Structure. 2008. PMID: 18462673 Free PMC article.

6

Mutational analysis of the Mu transposase. Contributions of two distinct regions of domain II to recombination.

Krementsova E, Giffin MJ, Pincus D, Baker TA. Krementsova E, et al. Among authors: giffin mj. J Biol Chem. 1998 Nov 20;273(47):31358-65. doi: 10.1074/jbc.273.47.31358. J Biol Chem. 1998. PMID: 9813045 Free article.

7

The analytical evaluation threshold for inorganic metal extractables and leachables analysis of medical devices.

Satori CP, Christensen CD, Street SM, Giffin M, Pohl CM, Christian WV. Satori CP, et al. Among authors: giffin m. Regul Toxicol Pharmacol. 2024 Dec;154:105725. doi: 10.1016/j.yrtph.2024.105725. Epub 2024 Oct 26. Regul Toxicol Pharmacol. 2024. PMID: 39490559 Free article.

8

The evolution and formalization of anesthesia assistant roles across Canada.

Yang H, Littleford J, Orser BA, Zaccagnini M, Umedaly H, Olsen M, Raazi M, LeDez K, Adam Law J, Giffin M, Foerster J, D'Souza B, Ali I, Dillane D, Christodoulou C, Buu N, Bryan R. Yang H, et al. Among authors: giffin m. Can J Anaesth. 2024 Sep 10. doi: 10.1007/s12630-024-02812-3. Online ahead of print. Can J Anaesth. 2024. PMID: 39256302 English.

9

Thermoplastic Toughening of a Semiaromatic Polyamide with an Amino-telechelic Polyethylene.

Giffin M, Plummer CJG, Frauenrath H. Giffin M, et al. ACS Appl Mater Interfaces. 2023 Jun 14;15(23):28430-28441. doi: 10.1021/acsami.3c00599. Epub 2023 Jun 2. ACS Appl Mater Interfaces. 2023. PMID: 37264775

10

AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer.

Giffin MJ, Cooke K, Lobenhofer EK, Estrada J, Zhan J, Deegen P, Thomas M, Murawsky CM, Werner J, Liu S, Lee F, Homann O, Friedrich M, Pearson JT, Raum T, Yang Y, Caenepeel S, Stevens J, Beltran PJ, Canon J, Coxon A, Bailis JM, Hughes PE. Giffin MJ, et al. Clin Cancer Res. 2021 Mar 1;27(5):1526-1537. doi: 10.1158/1078-0432.CCR-20-2845. Epub 2020 Nov 17. Clin Cancer Res. 2021. PMID: 33203642

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