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Novel second generation analogs of eribulin. Part III: Blood-brain barrier permeability and in vivo activity in a brain tumor model.
Narayan S, Carlson EM, Cheng H, Condon K, Du H, Eckley S, Hu Y, Jiang Y, Kumar V, Lewis BM, Saxton P, Schuck E, Seletsky BM, Tendyke K, Zhang H, Zheng W, Littlefield BA, Towle MJ, Yu MJ. Narayan S, et al. Among authors: saxton p. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1639-43. doi: 10.1016/j.bmcl.2011.01.096. Epub 2011 Jan 26. Bioorg Med Chem Lett. 2011. PMID: 21324687
Novel second generation analogs of eribulin. Part II: Orally available and active against resistant tumors in vivo.
Narayan S, Carlson EM, Cheng H, Condon K, Du H, Eckley S, Hu Y, Jiang Y, Kumar V, Lewis BM, Saxton P, Schuck E, Seletsky BM, Tendyke K, Zhang H, Zheng W, Littlefield BA, Towle MJ, Yu MJ. Narayan S, et al. Among authors: saxton p. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1634-8. doi: 10.1016/j.bmcl.2011.01.097. Epub 2011 Jan 25. Bioorg Med Chem Lett. 2011. PMID: 21324692
A high-performance liquid chromatography-tandem mass spectrometry method for the clinical combination study of carboplatin and anti-tumor agent eribulin mesylate (E7389) in human plasma.
Desjardins C, Saxton P, Lu SX, Li X, Rowbottom C, Wong YN. Desjardins C, et al. Among authors: saxton p. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Nov 15;875(2):373-82. doi: 10.1016/j.jchromb.2008.09.013. Epub 2008 Sep 19. J Chromatogr B Analyt Technol Biomed Life Sci. 2008. PMID: 18835754
77 results