Lin X - Search Results

1

Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans.

van de Leemput J, Chandran J, Knight MA, Holtzclaw LA, Scholz S, Cookson MR, Houlden H, Gwinn-Hardy K, Fung HC, Lin X, Hernandez D, Simon-Sanchez J, Wood NW, Giunti P, Rafferty I, Hardy J, Storey E, Gardner RJ, Forrest SM, Fisher EM, Russell JT, Cai H, Singleton AB. van de Leemput J, et al. Among authors: lin x. PLoS Genet. 2007 Jun;3(6):e108. doi: 10.1371/journal.pgen.0030108. Epub 2007 May 16. PLoS Genet. 2007. PMID: 17590087 Free PMC article.

2

The G59S mutation in p150(glued) causes dysfunction of dynactin in mice.

Lai C, Lin X, Chandran J, Shim H, Yang WJ, Cai H. Lai C, et al. Among authors: lin x. J Neurosci. 2007 Dec 19;27(51):13982-90. doi: 10.1523/JNEUROSCI.4226-07.2007. J Neurosci. 2007. PMID: 18094236 Free PMC article.

3

Deficiency in the ALS2 gene does not affect the motor neuron degeneration in SOD1(G93A) transgenic mice.

Lin X, Shim H, Cai H. Lin X, et al. Neurobiol Aging. 2007 Oct;28(10):1628-30. doi: 10.1016/j.neurobiolaging.2006.07.014. Epub 2006 Sep 12. Neurobiol Aging. 2007. PMID: 16973244 Free PMC article.

4

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking.

Lai C, Xie C, McCormack SG, Chiang HC, Michalak MK, Lin X, Chandran J, Shim H, Shimoji M, Cookson MR, Huganir RL, Rothstein JD, Price DL, Wong PC, Martin LJ, Zhu JJ, Cai H. Lai C, et al. Among authors: lin x. J Neurosci. 2006 Nov 8;26(45):11798-806. doi: 10.1523/JNEUROSCI.2084-06.2006. J Neurosci. 2006. PMID: 17093100 Free PMC article.

5

ALS2/alsin knockout mice and motor neuron diseases.

Cai H, Shim H, Lai C, Xie C, Lin X, Yang WJ, Chandran J. Cai H, et al. Among authors: lin x. Neurodegener Dis. 2008;5(6):359-66. doi: 10.1159/000151295. Epub 2008 Aug 20. Neurodegener Dis. 2008. PMID: 18714162 Free PMC article. Review.

6

Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function.

Chandran JS, Lin X, Zapata A, Höke A, Shimoji M, Moore SO, Galloway MP, Laird FM, Wong PC, Price DL, Bailey KR, Crawley JN, Shippenberg T, Cai H. Chandran JS, et al. Among authors: lin x. Neurobiol Dis. 2008 Mar;29(3):505-14. doi: 10.1016/j.nbd.2007.11.011. Epub 2007 Dec 4. Neurobiol Dis. 2008. PMID: 18187333 Free PMC article.

7

The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.

Wang L, Xie C, Greggio E, Parisiadou L, Shim H, Sun L, Chandran J, Lin X, Lai C, Yang WJ, Moore DJ, Dawson TM, Dawson VL, Chiosis G, Cookson MR, Cai H. Wang L, et al. Among authors: lin x. J Neurosci. 2008 Mar 26;28(13):3384-91. doi: 10.1523/JNEUROSCI.0185-08.2008. J Neurosci. 2008. PMID: 18367605 Free PMC article.

8

Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice.

Gu XL, Long CX, Sun L, Xie C, Lin X, Cai H. Gu XL, et al. Among authors: lin x. Mol Brain. 2010 Apr 21;3:12. doi: 10.1186/1756-6606-3-12. Mol Brain. 2010. PMID: 20409326 Free PMC article.

9

Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress.

Cai H, Lin X, Xie C, Laird FM, Lai C, Wen H, Chiang HC, Shim H, Farah MH, Hoke A, Price DL, Wong PC. Cai H, et al. Among authors: lin x. J Neurosci. 2005 Aug 17;25(33):7567-74. doi: 10.1523/JNEUROSCI.1645-05.2005. J Neurosci. 2005. PMID: 16107644 Free PMC article.

10

A calcineurin- and NFAT-dependent pathway is involved in α-synuclein-induced degeneration of midbrain dopaminergic neurons.

Luo J, Sun L, Lin X, Liu G, Yu J, Parisiadou L, Xie C, Ding J, Cai H. Luo J, et al. Among authors: lin x. Hum Mol Genet. 2014 Dec 15;23(24):6567-74. doi: 10.1093/hmg/ddu377. Epub 2014 Jul 22. Hum Mol Genet. 2014. PMID: 25051958 Free PMC article.

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