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Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils.
Chen K, Xu W, Wilson M, He B, Miller NW, Bengtén E, Edholm ES, Santini PA, Rath P, Chiu A, Cattalini M, Litzman J, B Bussel J, Huang B, Meini A, Riesbeck K, Cunningham-Rundles C, Plebani A, Cerutti A. Chen K, et al. Among authors: plebani a. Nat Immunol. 2009 Aug;10(8):889-98. doi: 10.1038/ni.1748. Epub 2009 Jun 28. Nat Immunol. 2009. PMID: 19561614 Free PMC article.
The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88.
He B, Santamaria R, Xu W, Cols M, Chen K, Puga I, Shan M, Xiong H, Bussel JB, Chiu A, Puel A, Reichenbach J, Marodi L, Döffinger R, Vasconcelos J, Issekutz A, Krause J, Davies G, Li X, Grimbacher B, Plebani A, Meffre E, Picard C, Cunningham-Rundles C, Casanova JL, Cerutti A. He B, et al. Among authors: plebani a. Nat Immunol. 2010 Sep;11(9):836-45. doi: 10.1038/ni.1914. Epub 2010 Aug 1. Nat Immunol. 2010. PMID: 20676093 Free PMC article.
B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen.
Puga I, Cols M, Barra CM, He B, Cassis L, Gentile M, Comerma L, Chorny A, Shan M, Xu W, Magri G, Knowles DM, Tam W, Chiu A, Bussel JB, Serrano S, Lorente JA, Bellosillo B, Lloreta J, Juanpere N, Alameda F, Baró T, de Heredia CD, Torán N, Català A, Torrebadell M, Fortuny C, Cusí V, Carreras C, Diaz GA, Blander JM, Farber CM, Silvestri G, Cunningham-Rundles C, Calvillo M, Dufour C, Notarangelo LD, Lougaris V, Plebani A, Casanova JL, Ganal SC, Diefenbach A, Aróstegui JI, Juan M, Yagüe J, Mahlaoui N, Donadieu J, Chen K, Cerutti A. Puga I, et al. Among authors: plebani a. Nat Immunol. 2011 Dec 25;13(2):170-80. doi: 10.1038/ni.2194. Nat Immunol. 2011. PMID: 22197976 Free PMC article.
A novel monoallelic gain of function mutation in p110δ causing atypical activated phosphoinositide 3-kinase δ syndrome (APDS-1).
Lougaris V, Baronio M, Moratto D, Tampella G, Gazzurelli L, Facchetti M, Martire B, Cardinale F, Lanzarotto F, Bondioni MP, Villanacci V, Grimbacher B, Plebani A. Lougaris V, et al. Among authors: plebani a. Clin Immunol. 2019 Mar;200:31-34. doi: 10.1016/j.clim.2019.01.003. Epub 2019 Jan 9. Clin Immunol. 2019. PMID: 30639166
C4b-binding protein (C4BP) activates B cells through the CD40 receptor.
Brodeur SR, Angelini F, Bacharier LB, Blom AM, Mizoguchi E, Fujiwara H, Plebani A, Notarangelo LD, Dahlback B, Tsitsikov E, Geha RS. Brodeur SR, et al. Among authors: plebani a. Immunity. 2003 Jun;18(6):837-48. doi: 10.1016/s1074-7613(03)00149-3. Immunity. 2003. PMID: 12818164 Free article.
416 results