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Pharmacokinetics, biodistribution and metabolism of squalenoyl adenosine nanoparticles in mice using dual radio-labeling and radio-HPLC analysis.
Gaudin A, Lepetre-Mouelhi S, Mougin J, Parrod M, Pieters G, Garcia-Argote S, Loreau O, Goncalves J, Chacun H, Courbebaisse Y, Clayette P, Desmaële D, Rousseau B, Andrieux K, Couvreur P. Gaudin A, et al. Among authors: chacun h. J Control Release. 2015 Aug 28;212:50-8. doi: 10.1016/j.jconrel.2015.06.016. Epub 2015 Jun 16. J Control Release. 2015. PMID: 26087468 Free PMC article.
A new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuary.
Skanji R, Andrieux K, Lalanne M, Caron J, Bourgaux C, Degrouard J, Brisset F, Gueutin C, Chacun H, Dereuddre-Bosquet N, Paci A, Vassal G, Bauduin L, Garcia-Argote S, Rousseau B, Clayette P, Desmaële D, Couvreur P. Skanji R, et al. Among authors: chacun h. Int J Pharm. 2011 Jul 29;414(1-2):285-97. doi: 10.1016/j.ijpharm.2011.05.005. Epub 2011 May 10. Int J Pharm. 2011. PMID: 21596125
Nanoencapsulation of a crystalline drug.
Layre AM, Gref R, Richard J, Requier D, Chacun H, Appel M, Domb AJ, Couvreur P. Layre AM, et al. Among authors: chacun h. Int J Pharm. 2005 Jul 25;298(2):323-7. doi: 10.1016/j.ijpharm.2005.02.039. Int J Pharm. 2005. PMID: 15899561
Squalenoylation favorably modifies the in vivo pharmacokinetics and biodistribution of gemcitabine in mice.
Reddy LH, Khoury H, Paci A, Deroussent A, Ferreira H, Dubernet C, Declèves X, Besnard M, Chacun H, Lepêtre-Mouelhi S, Desmaële D, Rousseau B, Laugier C, Cintrat JC, Vassal G, Couvreur P. Reddy LH, et al. Among authors: chacun h. Drug Metab Dispos. 2008 Aug;36(8):1570-7. doi: 10.1124/dmd.108.020735. Epub 2008 May 12. Drug Metab Dispos. 2008. PMID: 18474674
45 results