Howe PH - Search Results

1

Cell autonomous sorting and surface positioning in the formation of primitive endoderm in embryoid bodies.

Rula ME, Cai KQ, Moore R, Yang DH, Staub CM, Capo-Chichi CD, Jablonski SA, Howe PH, Smith ER, Xu XX. Rula ME, et al. Among authors: howe ph. Genesis. 2007 Jun;45(6):327-38. doi: 10.1002/dvg.20298. Genesis. 2007. PMID: 17506089

2

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway.

Hocevar BA, Smine A, Xu XX, Howe PH. Hocevar BA, et al. Among authors: howe ph. EMBO J. 2001 Jun 1;20(11):2789-801. doi: 10.1093/emboj/20.11.2789. EMBO J. 2001. PMID: 11387212 Free PMC article.

3

Disabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT).

Prunier C, Howe PH. Prunier C, et al. Among authors: howe ph. J Biol Chem. 2005 Apr 29;280(17):17540-8. doi: 10.1074/jbc.M500974200. Epub 2005 Feb 25. J Biol Chem. 2005. PMID: 15734730 Free article.

4

The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin.

Jiang Y, Prunier C, Howe PH. Jiang Y, et al. Among authors: howe ph. Oncogene. 2008 Mar 20;27(13):1865-75. doi: 10.1038/sj.onc.1210829. Epub 2007 Oct 8. Oncogene. 2008. PMID: 17922036 Free PMC article.

5

Disabled-2 (Dab2) mediates transforming growth factor beta (TGFbeta)-stimulated fibronectin synthesis through TGFbeta-activated kinase 1 and activation of the JNK pathway.

Hocevar BA, Prunier C, Howe PH. Hocevar BA, et al. Among authors: howe ph. J Biol Chem. 2005 Jul 8;280(27):25920-7. doi: 10.1074/jbc.M501150200. Epub 2005 May 12. J Biol Chem. 2005. PMID: 15894542 Free article.

6

Central role for disabled-2 in mesenchymal stem cardiac protein expression and functional consequences after engraftment in acute myocardial infarction.

Mayorga ME, Dong F, Sundararaman S, Huang Y, Jiang Y, Howe PH, Penn MS. Mayorga ME, et al. Among authors: howe ph. Stem Cells Dev. 2011 Apr;20(4):681-93. doi: 10.1089/scd.2010.0151. Epub 2010 Sep 13. Stem Cells Dev. 2011. PMID: 20666606

7

TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI.

Chaudhury A, Hussey GS, Ray PS, Jin G, Fox PL, Howe PH. Chaudhury A, et al. Among authors: howe ph. Nat Cell Biol. 2010 Mar;12(3):286-93. doi: 10.1038/ncb2029. Epub 2010 Feb 14. Nat Cell Biol. 2010. PMID: 20154680 Free PMC article.

8

Dab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactions.

Jiang Y, Luo W, Howe PH. Jiang Y, et al. Among authors: howe ph. Oncogene. 2009 Aug 20;28(33):2999-3007. doi: 10.1038/onc.2009.157. Epub 2009 Jul 6. Oncogene. 2009. PMID: 19581931 Free PMC article.

9

Regulation of the Wnt signaling pathway by disabled-2 (Dab2).

Hocevar BA, Mou F, Rennolds JL, Morris SM, Cooper JA, Howe PH. Hocevar BA, et al. Among authors: howe ph. EMBO J. 2003 Jun 16;22(12):3084-94. doi: 10.1093/emboj/cdg286. EMBO J. 2003. PMID: 12805222 Free PMC article.

10

Cathepsin-B-mediated cleavage of Disabled-2 regulates TGF-β-induced autophagy.

Jiang Y, Woosley AN, Sivalingam N, Natarajan S, Howe PH. Jiang Y, et al. Among authors: howe ph. Nat Cell Biol. 2016 Aug;18(8):851-63. doi: 10.1038/ncb3388. Epub 2016 Jul 11. Nat Cell Biol. 2016. PMID: 27398911 Free PMC article.

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