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A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation.
Martín-Subero JI, Ibbotson R, Klapper W, Michaux L, Callet-Bauchu E, Berger F, Calasanz MJ, De Wolf-Peeters C, Dyer MJ, Felman P, Gardiner A, Gascoyne RD, Gesk S, Harder L, Horsman DE, Kneba M, Küppers R, Majid A, Parry-Jones N, Ritgen M, Salido M, Solé F, Thiel G, Wacker HH, Oscier D, Wlodarska I, Siebert R. Martín-Subero JI, et al. Among authors: majid a. Leukemia. 2007 Jul;21(7):1532-44. doi: 10.1038/sj.leu.2404695. Epub 2007 May 10. Leukemia. 2007. PMID: 17495977
Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies.
Nagel I, Szczepanowski M, Martín-Subero JI, Harder L, Akasaka T, Ammerpohl O, Callet-Bauchu E, Gascoyne RD, Gesk S, Horsman D, Klapper W, Majid A, Martinez-Climent JA, Stilgenbauer S, Tönnies H, Dyer MJ, Siebert R. Nagel I, et al. Among authors: majid a. Blood. 2010 Aug 26;116(8):1317-20. doi: 10.1182/blood-2009-09-240440. Epub 2010 May 11. Blood. 2010. PMID: 20460502 Free article.
Male preponderance in chronic lymphocytic leukemia utilizing IGHV 1-69.
Walewska R, Majid A, Davis Z, Dusanjh P, Kennedy DB, Oscier DG, Dyer MJ. Walewska R, et al. Among authors: majid a. Leukemia. 2007 Dec;21(12):2537-8. doi: 10.1038/sj.leu.2404836. Epub 2007 Jun 28. Leukemia. 2007. PMID: 17597803 No abstract available.
Biallelic inactivation of TRAF3 in a subset of B-cell lymphomas with interstitial del(14)(q24.1q32.33).
Nagel I, Bug S, Tönnies H, Ammerpohl O, Richter J, Vater I, Callet-Bauchu E, Calasanz MJ, Martinez-Climent JA, Bastard C, Salido M, Schroers E, Martin-Subero JI, Gesk S, Harder L, Majid A, Dyer MJ, Siebert R. Nagel I, et al. Among authors: majid a. Leukemia. 2009 Nov;23(11):2153-5. doi: 10.1038/leu.2009.149. Epub 2009 Aug 20. Leukemia. 2009. PMID: 19693093 No abstract available.
A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact.
Queirós AC, Villamor N, Clot G, Martinez-Trillos A, Kulis M, Navarro A, Penas EM, Jayne S, Majid A, Richter J, Bergmann AK, Kolarova J, Royo C, Russiñol N, Castellano G, Pinyol M, Bea S, Salaverria I, López-Guerra M, Colomer D, Aymerich M, Rozman M, Delgado J, Giné E, González-Díaz M, Puente XS, Siebert R, Dyer MJ, López-Otín C, Rozman C, Campo E, López-Guillermo A, Martín-Subero JI. Queirós AC, et al. Among authors: majid a. Leukemia. 2015 Mar;29(3):598-605. doi: 10.1038/leu.2014.252. Epub 2014 Aug 25. Leukemia. 2015. PMID: 25151957
t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).
Russell LJ, Akasaka T, Majid A, Sugimoto KJ, Loraine Karran E, Nagel I, Harder L, Claviez A, Gesk S, Moorman AV, Ross F, Mazzullo H, Strefford JC, Siebert R, Dyer MJ, Harrison CJ. Russell LJ, et al. Among authors: majid a. Blood. 2008 Jan 1;111(1):387-91. doi: 10.1182/blood-2007-07-092015. Epub 2007 Oct 16. Blood. 2008. PMID: 17940204 Free article.
Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).
Akasaka T, Balasas T, Russell LJ, Sugimoto KJ, Majid A, Walewska R, Karran EL, Brown DG, Cain K, Harder L, Gesk S, Martin-Subero JI, Atherton MG, Brüggemann M, Calasanz MJ, Davies T, Haas OA, Hagemeijer A, Kempski H, Lessard M, Lillington DM, Moore S, Nguyen-Khac F, Radford-Weiss I, Schoch C, Struski S, Talley P, Welham MJ, Worley H, Strefford JC, Harrison CJ, Siebert R, Dyer MJ. Akasaka T, et al. Among authors: majid a. Blood. 2007 Apr 15;109(8):3451-61. doi: 10.1182/blood-2006-08-041012. Epub 2006 Dec 14. Blood. 2007. PMID: 17170124 Free article. Clinical Trial.
929 results