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High avidity antigen-specific CTL identified by CD8-independent tetramer staining.
Choi EM, Chen JL, Wooldridge L, Salio M, Lissina A, Lissin N, Hermans IF, Silk JD, Mirza F, Palmowski MJ, Dunbar PR, Jakobsen BK, Sewell AK, Cerundolo V. Choi EM, et al. Among authors: dunbar pr. J Immunol. 2003 Nov 15;171(10):5116-23. doi: 10.4049/jimmunol.171.10.5116. J Immunol. 2003. PMID: 14607910
Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: this is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface.
Wooldridge L, Hutchinson SL, Choi EM, Lissina A, Jones E, Mirza F, Dunbar PR, Price DA, Cerundolo V, Sewell AK. Wooldridge L, et al. Among authors: dunbar pr. J Immunol. 2003 Dec 15;171(12):6650-60. doi: 10.4049/jimmunol.171.12.6650. J Immunol. 2003. PMID: 14662868
Novel CD8+ T cell antagonists based on beta 2-microglobulin.
Glick M, Price DA, Vuidepot AL, Andersen TB, Hutchinson SL, Laugel B, Sewell AK, Boulter JM, Dunbar PR, Cerundolo V, Oxenius A, Bell JI, Richards WG, Jakobsen BK. Glick M, et al. Among authors: dunbar pr. J Biol Chem. 2002 Jun 7;277(23):20840-6. doi: 10.1074/jbc.M201819200. Epub 2002 Mar 25. J Biol Chem. 2002. PMID: 11914379 Free article.
Structural and kinetic basis for heightened immunogenicity of T cell vaccines.
Chen JL, Stewart-Jones G, Bossi G, Lissin NM, Wooldridge L, Choi EM, Held G, Dunbar PR, Esnouf RM, Sami M, Boulter JM, Rizkallah P, Renner C, Sewell A, van der Merwe PA, Jakobsen BK, Griffiths G, Jones EY, Cerundolo V. Chen JL, et al. Among authors: dunbar pr. J Exp Med. 2005 Apr 18;201(8):1243-55. doi: 10.1084/jem.20042323. J Exp Med. 2005. PMID: 15837811 Free PMC article.
A novel approach to antigen-specific deletion of CTL with minimal cellular activation using alpha3 domain mutants of MHC class I/peptide complex.
Xu XN, Purbhoo MA, Chen N, Mongkolsapaya J, Cox JH, Meier UC, Tafuro S, Dunbar PR, Sewell AK, Hourigan CS, Appay V, Cerundolo V, Burrows SR, McMichael AJ, Screaton GR. Xu XN, et al. Among authors: dunbar pr. Immunity. 2001 May;14(5):591-602. doi: 10.1016/s1074-7613(01)00133-9. Immunity. 2001. PMID: 11371361 Free article.
144 results