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TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells.
Zirlik A, Bavendiek U, Libby P, MacFarlane L, Gerdes N, Jagielska J, Ernst S, Aikawa M, Nakano H, Tsitsikov E, Schönbeck U. Zirlik A, et al. Among authors: ernst s. Arterioscler Thromb Vasc Biol. 2007 May;27(5):1101-7. doi: 10.1161/ATVBAHA.107.140566. Epub 2007 Mar 1. Arterioscler Thromb Vasc Biol. 2007. PMID: 17332487
CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1.
Zirlik A, Maier C, Gerdes N, MacFarlane L, Soosairajah J, Bavendiek U, Ahrens I, Ernst S, Bassler N, Missiou A, Patko Z, Aikawa M, Schönbeck U, Bode C, Libby P, Peter K. Zirlik A, et al. Among authors: ernst s. Circulation. 2007 Mar 27;115(12):1571-80. doi: 10.1161/CIRCULATIONAHA.106.683201. Epub 2007 Mar 19. Circulation. 2007. PMID: 17372166
Tumor necrosis factor receptor-associated factor 1 (TRAF1) deficiency attenuates atherosclerosis in mice by impairing monocyte recruitment to the vessel wall.
Missiou A, Köstlin N, Varo N, Rudolf P, Aichele P, Ernst S, Münkel C, Walter C, Stachon P, Sommer B, Pfeifer D, Zirlik K, MacFarlane L, Wolf D, Tsitsikov E, Bode C, Libby P, Zirlik A. Missiou A, et al. Among authors: ernst s. Circulation. 2010 May 11;121(18):2033-44. doi: 10.1161/CIRCULATIONAHA.109.895037. Epub 2010 Apr 26. Circulation. 2010. PMID: 20421522 Free PMC article.
TRAF5 deficiency accelerates atherogenesis in mice by increasing inflammatory cell recruitment and foam cell formation.
Missiou A, Rudolf P, Stachon P, Wolf D, Varo N, Aichele P, Colberg C, Hoppe N, Ernst S, Münkel C, Walter C, Sommer B, Hilgendorf I, Nakano H, Bode C, Zirlik A. Missiou A, et al. Among authors: ernst s. Circ Res. 2010 Sep 17;107(6):757-66. doi: 10.1161/CIRCRESAHA.110.219295. Epub 2010 Jul 22. Circ Res. 2010. PMID: 20651286 Clinical Trial.
924 results