Gharibyan V - Search Results

1

RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis.

Boumber YA, Kondo Y, Chen X, Shen L, Gharibyan V, Konishi K, Estey E, Kantarjian H, Garcia-Manero G, Issa JP. Boumber YA, et al. Among authors: gharibyan v. Cancer Res. 2007 Mar 1;67(5):1997-2005. doi: 10.1158/0008-5472.CAN-06-3093. Cancer Res. 2007. PMID: 17332327

2

DNA methylation does not stably lock gene expression but instead serves as a molecular mark for gene silencing memory.

Raynal NJ, Si J, Taby RF, Gharibyan V, Ahmed S, Jelinek J, Estécio MR, Issa JP. Raynal NJ, et al. Among authors: gharibyan v. Cancer Res. 2012 Mar 1;72(5):1170-81. doi: 10.1158/0008-5472.CAN-11-3248. Epub 2012 Jan 4. Cancer Res. 2012. PMID: 22219169 Free PMC article.

3

Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer.

Raynal NJ, Lee JT, Wang Y, Beaudry A, Madireddi P, Garriga J, Malouf GG, Dumont S, Dettman EJ, Gharibyan V, Ahmed S, Chung W, Childers WE, Abou-Gharbia M, Henry RA, Andrews AJ, Jelinek J, Cui Y, Baylin SB, Gill DL, Issa JP. Raynal NJ, et al. Among authors: gharibyan v. Cancer Res. 2016 Mar 15;76(6):1494-505. doi: 10.1158/0008-5472.CAN-14-2391. Epub 2015 Dec 30. Cancer Res. 2016. PMID: 26719529 Free PMC article.

4

Phase II study of low-dose decitabine in combination with imatinib mesylate in patients with accelerated or myeloid blastic phase of chronic myelogenous leukemia.

Oki Y, Kantarjian HM, Gharibyan V, Jones D, O'brien S, Verstovsek S, Cortes J, Morris GM, Garcia-Manero G, Issa JP. Oki Y, et al. Among authors: gharibyan v. Cancer. 2007 Mar 1;109(5):899-906. doi: 10.1002/cncr.22470. Cancer. 2007. PMID: 17236224 Free article. Clinical Trial.

5

Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia.

Jelinek J, Gharibyan V, Estecio MR, Kondo K, He R, Chung W, Lu Y, Zhang N, Liang S, Kantarjian HM, Cortes JE, Issa JP. Jelinek J, et al. Among authors: gharibyan v. PLoS One. 2011;6(7):e22110. doi: 10.1371/journal.pone.0022110. Epub 2011 Jul 8. PLoS One. 2011. PMID: 21760961 Free PMC article.

6

Impact of aberrant DNA methylation patterns including CYP1B1 methylation in adolescents and young adults with acute lymphocytic leukemia.

DiNardo CD, Gharibyan V, Yang H, Wei Y, Pierce S, Kantarjian HM, Garcia-Manero G, Rytting M. DiNardo CD, et al. Among authors: gharibyan v. Am J Hematol. 2013 Sep;88(9):784-9. doi: 10.1002/ajh.23511. Epub 2013 Jul 23. Am J Hematol. 2013. PMID: 23757320 Free PMC article.

7

Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate.

Issa JP, Gharibyan V, Cortes J, Jelinek J, Morris G, Verstovsek S, Talpaz M, Garcia-Manero G, Kantarjian HM. Issa JP, et al. Among authors: gharibyan v. J Clin Oncol. 2005 Jun 10;23(17):3948-56. doi: 10.1200/JCO.2005.11.981. Epub 2005 May 9. J Clin Oncol. 2005. PMID: 15883410 Clinical Trial.

8

JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia.

Jelinek J, Oki Y, Gharibyan V, Bueso-Ramos C, Prchal JT, Verstovsek S, Beran M, Estey E, Kantarjian HM, Issa JP. Jelinek J, et al. Among authors: gharibyan v. Blood. 2005 Nov 15;106(10):3370-3. doi: 10.1182/blood-2005-05-1800. Epub 2005 Jul 21. Blood. 2005. PMID: 16037387 Free PMC article.

9

LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability.

Estécio MR, Gharibyan V, Shen L, Ibrahim AE, Doshi K, He R, Jelinek J, Yang AS, Yan PS, Huang TH, Tajara EH, Issa JP. Estécio MR, et al. Among authors: gharibyan v. PLoS One. 2007 May 2;2(5):e399. doi: 10.1371/journal.pone.0000399. PLoS One. 2007. PMID: 17476321 Free PMC article.

10

Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees.

Spannhoff A, Kim YK, Raynal NJ, Gharibyan V, Su MB, Zhou YY, Li J, Castellano S, Sbardella G, Issa JP, Bedford MT. Spannhoff A, et al. Among authors: gharibyan v. EMBO Rep. 2011 Mar;12(3):238-43. doi: 10.1038/embor.2011.9. Epub 2011 Feb 18. EMBO Rep. 2011. PMID: 21331099 Free PMC article.

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