Kaufmann T - Search Results

1

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.

Willis SN, Fletcher JI, Kaufmann T, van Delft MF, Chen L, Czabotar PE, Ierino H, Lee EF, Fairlie WD, Bouillet P, Strasser A, Kluck RM, Adams JM, Huang DC. Willis SN, et al. Among authors: kaufmann t. Science. 2007 Feb 9;315(5813):856-9. doi: 10.1126/science.1133289. Science. 2007. PMID: 17289999

2

Consequences of the combined loss of BOK and BAK or BOK and BAX.

Ke F, Bouillet P, Kaufmann T, Strasser A, Kerr J, Voss AK. Ke F, et al. Among authors: kaufmann t. Cell Death Dis. 2013 Jun 6;4(6):e650. doi: 10.1038/cddis.2013.176. Cell Death Dis. 2013. PMID: 23744350 Free PMC article.

3

Proapoptotic BH3-only protein Bid is essential for death receptor-induced apoptosis of pancreatic beta-cells.

McKenzie MD, Carrington EM, Kaufmann T, Strasser A, Huang DC, Kay TW, Allison J, Thomas HE. McKenzie MD, et al. Among authors: kaufmann t. Diabetes. 2008 May;57(5):1284-92. doi: 10.2337/db07-1692. Epub 2008 Feb 5. Diabetes. 2008. PMID: 18252892

4

BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice.

Ke F, Voss A, Kerr JB, O'Reilly LA, Tai L, Echeverry N, Bouillet P, Strasser A, Kaufmann T. Ke F, et al. Among authors: kaufmann t. Cell Death Differ. 2012 Jun;19(6):915-25. doi: 10.1038/cdd.2011.210. Epub 2012 Jan 27. Cell Death Differ. 2012. PMID: 22281706 Free PMC article.

5

Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.

Kaufmann T, Jost PJ, Pellegrini M, Puthalakath H, Gugasyan R, Gerondakis S, Cretney E, Smyth MJ, Silke J, Hakem R, Bouillet P, Mak TW, Dixit VM, Strasser A. Kaufmann T, et al. Immunity. 2009 Jan 16;30(1):56-66. doi: 10.1016/j.immuni.2008.10.017. Immunity. 2009. PMID: 19119023 Free PMC article.

6

MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation.

O'Reilly LA, Kruse EA, Puthalakath H, Kelly PN, Kaufmann T, Huang DC, Strasser A. O'Reilly LA, et al. Among authors: kaufmann t. J Immunol. 2009 Jul 1;183(1):261-9. doi: 10.4049/jimmunol.0803853. J Immunol. 2009. PMID: 19542438 Free PMC article.

7

XIAP discriminates between type I and type II FAS-induced apoptosis.

Jost PJ, Grabow S, Gray D, McKenzie MD, Nachbur U, Huang DC, Bouillet P, Thomas HE, Borner C, Silke J, Strasser A, Kaufmann T. Jost PJ, et al. Among authors: kaufmann t. Nature. 2009 Aug 20;460(7258):1035-9. doi: 10.1038/nature08229. Epub 2009 Jul 22. Nature. 2009. PMID: 19626005 Free PMC article.

8

Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein.

Herold MJ, Rohrbeck L, Lang MJ, Grumont R, Gerondakis S, Tai L, Bouillet P, Kaufmann T, Strasser A. Herold MJ, et al. Among authors: kaufmann t. EMBO Rep. 2013 Nov;14(11):992-8. doi: 10.1038/embor.2013.152. Epub 2013 Sep 24. EMBO Rep. 2013. PMID: 24060902 Free PMC article.

9

Is BOK required for apoptosis induced by endoplasmic reticulum stress?

Fernandez-Marrero Y, Ke F, Echeverry N, Bouillet P, Bachmann D, Strasser A, Kaufmann T. Fernandez-Marrero Y, et al. Among authors: kaufmann t. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E492-3. doi: 10.1073/pnas.1516347113. Epub 2016 Jan 25. Proc Natl Acad Sci U S A. 2016. PMID: 26811499 Free PMC article. No abstract available.

10

Apaf-1 and caspase-9 are required for cytokine withdrawal-induced apoptosis of mast cells but dispensable for their functional and clonogenic death.

Marsden VS, Kaufmann T, O'reilly LA, Adams JM, Strasser A. Marsden VS, et al. Among authors: kaufmann t. Blood. 2006 Mar 1;107(5):1872-7. doi: 10.1182/blood-2005-05-2160. Epub 2005 Nov 15. Blood. 2006. PMID: 16291596 Free article.

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