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Apomine, a novel hypocholesterolemic agent, accelerates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and stimulates low density lipoprotein receptor activity.
Roitelman J, Masson D, Avner R, Ammon-Zufferey C, Perez A, Guyon-Gellin Y, Bentzen CL, Niesor EJ. Roitelman J, et al. Among authors: guyon gellin y. J Biol Chem. 2004 Feb 20;279(8):6465-73. doi: 10.1074/jbc.M308094200. Epub 2003 Nov 19. J Biol Chem. 2004. PMID: 14627708 Free article.