Edwards CM - Search Results

1

Apomine, an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo.

Edwards CM, Mueller G, Roelofs AJ, Chantry A, Perry M, Russell RG, Van Camp B, Guyon-Gellin Y, Niesor EJ, Bentzen CL, Vanderkerken K, Croucher PI. Edwards CM, et al. Int J Cancer. 2007 Apr 15;120(8):1657-63. doi: 10.1002/ijc.22478. Int J Cancer. 2007. PMID: 17230522

2

Apomine enhances the antitumor effects of lovastatin on myeloma cells by down-regulating 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

Roelofs AJ, Edwards CM, Russell RG, Ebetino FH, Rogers MJ, Hulley PA. Roelofs AJ, et al. Among authors: edwards cm. J Pharmacol Exp Ther. 2007 Jul;322(1):228-35. doi: 10.1124/jpet.106.116467. Epub 2007 Apr 5. J Pharmacol Exp Ther. 2007. PMID: 17412884 Free PMC article.

3

Selective targeting of death receptor 5 circumvents resistance of MG-63 osteosarcoma cells to TRAIL-induced apoptosis.

Locklin RM, Federici E, Espina B, Hulley PA, Russell RG, Edwards CM. Locklin RM, et al. Among authors: edwards cm. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3219-28. doi: 10.1158/1535-7163.MCT-07-0275. Epub 2007 Dec 7. Mol Cancer Ther. 2007. PMID: 18065493 Free PMC article.

4

Tumor-host cell interactions in the bone disease of myeloma.

Fowler JA, Edwards CM, Croucher PI. Fowler JA, et al. Among authors: edwards cm. Bone. 2011 Jan;48(1):121-8. doi: 10.1016/j.bone.2010.06.029. Epub 2010 Jul 13. Bone. 2011. PMID: 20615487 Free PMC article. Review.

5

Contributions of the host microenvironment to cancer-induced bone disease.

Olechnowicz SW, Edwards CM. Olechnowicz SW, et al. Among authors: edwards cm. Cancer Res. 2014 Mar 15;74(6):1625-31. doi: 10.1158/0008-5472.CAN-13-2645. Epub 2014 Mar 5. Cancer Res. 2014. PMID: 24599133 Free PMC article. Review.

6

Novel therapeutic targets in myeloma bone disease.

Webb SL, Edwards CM. Webb SL, et al. Among authors: edwards cm. Br J Pharmacol. 2014 Aug;171(16):3765-76. doi: 10.1111/bph.12742. Br J Pharmacol. 2014. PMID: 24750110 Free PMC article. Review.

7

A loss of host-derived MMP-7 promotes myeloma growth and osteolytic bone disease in vivo.

Lwin ST, Fowler JA, Drake MT, Edwards JR, Lynch CC, Edwards CM. Lwin ST, et al. Among authors: edwards cm, edwards jr. Mol Cancer. 2017 Feb 28;16(1):49. doi: 10.1186/s12943-017-0616-9. Mol Cancer. 2017. PMID: 28241871 Free PMC article.

8

Myeloma Cells Down-Regulate Adiponectin in Bone Marrow Adipocytes Via TNF-Alpha.

Morris EV, Suchacki KJ, Hocking J, Cartwright R, Sowman A, Gamez B, Lea R, Drake MT, Cawthorn WP, Edwards CM. Morris EV, et al. Among authors: edwards cm. J Bone Miner Res. 2020 May;35(5):942-955. doi: 10.1002/jbmr.3951. Epub 2020 Jan 16. J Bone Miner Res. 2020. PMID: 31886918 Free PMC article.

9

Advances in the molecular pharmacology of bone and cancer-related bone diseases.

Edwards CM, Russell RGG. Edwards CM, et al. Br J Pharmacol. 2021 May;178(9):1889-1890. doi: 10.1111/bph.15431. Br J Pharmacol. 2021. PMID: 33860527 Free article. No abstract available.

10

Bone marrow stromal cells create a permissive microenvironment for myeloma development: a new stromal role for Wnt inhibitor Dkk1.

Fowler JA, Mundy GR, Lwin ST, Edwards CM. Fowler JA, et al. Among authors: edwards cm. Cancer Res. 2012 May 1;72(9):2183-9. doi: 10.1158/0008-5472.CAN-11-2067. Epub 2012 Feb 28. Cancer Res. 2012. PMID: 22374979 Free PMC article.

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