Denison MS - Search Results

1

Structural and functional characterization of the aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis.

Pandini A, Denison MS, Song Y, Soshilov AA, Bonati L. Pandini A, et al. Among authors: denison ms. Biochemistry. 2007 Jan 23;46(3):696-708. doi: 10.1021/bi061460t. Biochemistry. 2007. PMID: 17223691 Free PMC article.

2

Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis.

Pandini A, Soshilov AA, Song Y, Zhao J, Bonati L, Denison MS. Pandini A, et al. Among authors: denison ms. Biochemistry. 2009 Jun 30;48(25):5972-83. doi: 10.1021/bi900259z. Biochemistry. 2009. PMID: 19456125 Free PMC article.

3

New aryl hydrocarbon receptor homology model targeted to improve docking reliability.

Motto I, Bordogna A, Soshilov AA, Denison MS, Bonati L. Motto I, et al. Among authors: denison ms. J Chem Inf Model. 2011 Nov 28;51(11):2868-81. doi: 10.1021/ci2001617. Epub 2011 Nov 2. J Chem Inf Model. 2011. PMID: 21981577 Free PMC article.

4

Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor.

Fraccalvieri D, Soshilov AA, Karchner SI, Franks DG, Pandini A, Bonati L, Hahn ME, Denison MS. Fraccalvieri D, et al. Among authors: denison ms. Biochemistry. 2013 Jan 29;52(4):714-25. doi: 10.1021/bi301457f. Epub 2013 Jan 14. Biochemistry. 2013. PMID: 23286227 Free PMC article.

5

Specific ligand binding domain residues confer low dioxin responsiveness to AHR1β of Xenopus laevis.

Odio C, Holzman SA, Denison MS, Fraccalvieri D, Bonati L, Franks DG, Hahn ME, Powell WH. Odio C, et al. Among authors: denison ms. Biochemistry. 2013 Mar 12;52(10):1746-54. doi: 10.1021/bi301722k. Epub 2013 Feb 27. Biochemistry. 2013. PMID: 23394719 Free PMC article.

6

Structural modeling of the AhR:ARNT complex in the bHLH-PASA-PASB region elucidates the key determinants of dimerization.

Corrada D, Denison MS, Bonati L. Corrada D, et al. Among authors: denison ms. Mol Biosyst. 2017 May 2;13(5):981-990. doi: 10.1039/c7mb00005g. Mol Biosyst. 2017. PMID: 28393157 Free PMC article.

7

Transitional States in Ligand-Dependent Transformation of the Aryl Hydrocarbon Receptor into Its DNA-Binding Form.

Soshilov AA, Motta S, Bonati L, Denison MS. Soshilov AA, et al. Among authors: denison ms. Int J Mol Sci. 2020 Apr 2;21(7):2474. doi: 10.3390/ijms21072474. Int J Mol Sci. 2020. PMID: 32252465 Free PMC article.

8

Ligand binding and activation of the Ah receptor.

Denison MS, Pandini A, Nagy SR, Baldwin EP, Bonati L. Denison MS, et al. Chem Biol Interact. 2002 Sep 20;141(1-2):3-24. doi: 10.1016/s0009-2797(02)00063-7. Chem Biol Interact. 2002. PMID: 12213382 Free article. Review.

9

Role of the Per/Arnt/Sim domains in ligand-dependent transformation of the aryl hydrocarbon receptor.

Soshilov A, Denison MS. Soshilov A, et al. Among authors: denison ms. J Biol Chem. 2008 Nov 21;283(47):32995-3005. doi: 10.1074/jbc.M802414200. Epub 2008 Sep 19. J Biol Chem. 2008. PMID: 18806268 Free PMC article.

10

Ligand displaces heat shock protein 90 from overlapping binding sites within the aryl hydrocarbon receptor ligand-binding domain.

Soshilov A, Denison MS. Soshilov A, et al. Among authors: denison ms. J Biol Chem. 2011 Oct 7;286(40):35275-82. doi: 10.1074/jbc.M111.246439. Epub 2011 Aug 19. J Biol Chem. 2011. PMID: 21856752 Free PMC article.

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