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Cadmium chloride, benzo[a]pyrene and cyclophosphamide tested in the in vitro mammalian cell micronucleus test (MNvit) in the human lymphoblastoid cell line TK6 at Covance laboratories, Harrogate UK in support of OECD draft Test Guideline 487.
Fowler P, Whitwell J, Jeffrey L, Young J, Smith K, Kirkland D. Fowler P, et al. Among authors: whitwell j. Mutat Res. 2010 Oct 29;702(2):171-4. doi: 10.1016/j.mrgentox.2010.02.016. Epub 2010 Mar 3. Mutat Res. 2010. PMID: 20206291
Etoposide; colchicine; mitomycin C and cyclophosphamide tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster lung (CHL) cells at Covance laboratories; Harrogate UK in support of OECD draft Test Guideline 487.
Fowler P, Whitwell J, Jeffrey L, Young J, Smith K, Kirkland D. Fowler P, et al. Among authors: whitwell j. Mutat Res. 2010 Oct 29;702(2):175-80. doi: 10.1016/j.mrgentox.2010.02.018. Epub 2010 Mar 10. Mutat Res. 2010. PMID: 20226265
A comparison of the lowest effective concentration in culture media for detection of chromosomal damage in vitro and in blood or plasma for detection of micronuclei in vivo.
Kirkland D, Whitwell J, Smith R, Hashimoto K, Ji Z, Kenny J, Koyama N, Lovell DP, Martus HJ, Meurer K, Roberts D, Takeiri A, Uno Y, van der Leede BJ, White P, Zeller A. Kirkland D, et al. Among authors: whitwell j. Mutat Res Genet Toxicol Environ Mutagen. 2022 Jul-Aug;879-880:503503. doi: 10.1016/j.mrgentox.2022.503503. Epub 2022 May 28. Mutat Res Genet Toxicol Environ Mutagen. 2022. PMID: 35914859 Free article.
Evaluation of a multi-endpoint assay in rats, combining the bone-marrow micronucleus test, the Comet assay and the flow-cytometric peripheral blood micronucleus test.
Bowen DE, Whitwell JH, Lillford L, Henderson D, Kidd D, Mc Garry S, Pearce G, Beevers C, Kirkland DJ; Work conducted at Covance Laboratories Ltd., Harrogate. Bowen DE, et al. Among authors: whitwell jh. Mutat Res. 2011 May 18;722(1):7-19. doi: 10.1016/j.mrgentox.2011.02.009. Epub 2011 Feb 25. Mutat Res. 2011. PMID: 21356328
5-Fluorouracil, colchicine, benzo[a]pyrene and cytosine arabinoside tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster V79 cells at Covance Laboratories, Harrogate, UK in support of OECD draft Test Guideline 487.
Whitwell J, Fowler P, Allars S, Jenner K, Lloyd M, Wood D, Smith K, Young J, Jeffrey L, Kirkland D. Whitwell J, et al. Mutat Res. 2010 Oct 29;702(2):230-6. doi: 10.1016/j.mrgentox.2010.04.022. Epub 2010 May 11. Mutat Res. 2010. PMID: 20438860
2-Aminoanthracene, 5-fluorouracil, colchicine, benzo[a]pyrene, cadmium chloride and cytosine arabinoside tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster ovary (CHO) cells at Covance Laboratories, Harrogate UK in support of OECD draft Test Guideline 487.
Whitwell J, Fowler P, Allars S, Jenner K, Lloyd M, Wood D, Smith K, Young J, Jeffrey L, Kirkland D. Whitwell J, et al. Mutat Res. 2010 Oct 29;702(2):237-47. doi: 10.1016/j.mrgentox.2010.05.004. Epub 2010 May 15. Mutat Res. 2010. PMID: 20478394
Relationships between p53 status, apoptosis and induction of micronuclei in different human and mouse cell lines in vitro: Implications for improving existing assays.
Whitwell J, Smith R, Jenner K, Lyon H, Wood D, Clements J, Aschcroft-Hawley K, Gollapudi B, Kirkland D, Lorge E, Pfuhler S, Tanir JY, Thybaud V. Whitwell J, et al. Mutat Res Genet Toxicol Environ Mutagen. 2015 Aug;789-790:7-27. doi: 10.1016/j.mrgentox.2015.05.011. Epub 2015 May 30. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 26232254
448 results