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833 results

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Page 1
Development of chemokine receptor CXCR4 antagonists using bio-mimetic strategy.
Tamamura H, Tanaka T, Tsutsumi H, Ohashi N, Hiramatsu K, Araki T, Ojida A, Hamachi I, Wang Z, Peiper SC, Trent JO, Ueda S, Oishi S, Fujii N. Tamamura H, et al. Among authors: oishi s. Adv Exp Med Biol. 2009;611:145-6. doi: 10.1007/978-0-387-73657-0_65. Adv Exp Med Biol. 2009. PMID: 19400132 No abstract available.
Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids.
Tanaka T, Nomura W, Narumi T, Esaka A, Oishi S, Ohashi N, Itotani K, Evans BJ, Wang ZX, Peiper SC, Fujii N, Tamamura H. Tanaka T, et al. Among authors: oishi s. Org Biomol Chem. 2009 Sep 21;7(18):3805-9. doi: 10.1039/b908286g. Epub 2009 Jul 20. Org Biomol Chem. 2009. PMID: 19707686
Certification of the critical importance of L-3-(2-naphthyl)alanine at position 3 of a specific CXCR4 inhibitor, T140, leads to an exploratory performance of its downsizing study.
Tamamura H, Omagari A, Hiramatsu K, Oishi S, Habashita H, Kanamoto T, Gotoh K, Yamamoto N, Nakashima H, Otaka A, Fujii N. Tamamura H, et al. Among authors: oishi s. Bioorg Med Chem. 2002 May;10(5):1417-26. doi: 10.1016/s0968-0896(01)00419-9. Bioorg Med Chem. 2002. PMID: 11886804
Synthesis and evaluation of pseudopeptide analogues of a specific CXCR4 inhibitor, T140: the insertion of an (E)-alkene dipeptide isostere into the betaII'-turn moiety.
Tamamura H, Hiramatsu K, Miyamoto K, Omagari A, Oishi S, Nakashima H, Yamamoto N, Kuroda Y, Nakagawa T, Otaka A, Fujii N. Tamamura H, et al. Among authors: oishi s. Bioorg Med Chem Lett. 2002 Mar 25;12(6):923-8. doi: 10.1016/s0960-894x(02)00041-0. Bioorg Med Chem Lett. 2002. PMID: 11958995
Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries.
Fujii N, Oishi S, Hiramatsu K, Araki T, Ueda S, Tamamura H, Otaka A, Kusano S, Terakubo S, Nakashima H, Broach JA, Trent JO, Wang ZX, Peiper SC. Fujii N, et al. Among authors: oishi s. Angew Chem Int Ed Engl. 2003 Jul 21;42(28):3251-3. doi: 10.1002/anie.200351024. Angew Chem Int Ed Engl. 2003. PMID: 12876735 No abstract available.
Stereoselective synthesis of 3,6-disubstituted-3,6-dihydropyridin-2-ones as potential diketopiperazine mimetics using organocopper-mediated anti-SN2' reactions and their use in the preparation of low-molecule CXCR4 antagonists.
Niida A, Tanigaki H, Inokuchi E, Sasaki Y, Oishi S, Ohno H, Tamamura H, Wang Z, Peiper SC, Kitaura K, Otaka A, Fujii N. Niida A, et al. Among authors: oishi s. J Org Chem. 2006 May 12;71(10):3942-51. doi: 10.1021/jo060390t. J Org Chem. 2006. PMID: 16674071
833 results