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Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression.
Kim SJ, Winter K, Nian C, Tsuneoka M, Koda Y, McIntosh CH. Kim SJ, et al. Among authors: mcintosh ch. J Biol Chem. 2005 Jun 10;280(23):22297-307. doi: 10.1074/jbc.M500540200. Epub 2005 Apr 6. J Biol Chem. 2005. PMID: 15817464 Free article.
175 results