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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, Vassiliou LV, Kolettas E, Niforou K, Zoumpourlis VC, Takaoka M, Nakagawa H, Tort F, Fugger K, Johansson F, Sehested M, Andersen CL, Dyrskjot L, Ørntoft T, Lukas J, Kittas C, Helleday T, Halazonetis TD, Bartek J, Gorgoulis VG. Bartkova J, et al. Among authors: gorgoulis vg. Nature. 2006 Nov 30;444(7119):633-7. doi: 10.1038/nature05268. Nature. 2006. PMID: 17136093
Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. WAFI/Cip1 = WAF1/Cip1.
Zacharatos PV, Gorgoulis VG, Kotsinas A, Manolis EN, Liloglou T, Rassidakis AN, Kanavaros P, Field JD, Halazonetis T, Kittas C. Zacharatos PV, et al. Among authors: gorgoulis vg. Anticancer Res. 1999 Jan-Feb;19(1A):579-87. Anticancer Res. 1999. PMID: 10226602
349 results