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The functional variant of the inhibitory Fcgamma receptor IIb (CD32B) is associated with the rate of radiologic joint damage and dendritic cell function in rheumatoid arthritis.
Radstake TR, Franke B, Wenink MH, Nabbe KC, Coenen MJ, Welsing P, Bonvini E, Koenig S, van den Berg WB, Barrera P, van Riel PL. Radstake TR, et al. Among authors: nabbe kc. Arthritis Rheum. 2006 Dec;54(12):3828-37. doi: 10.1002/art.22275. Arthritis Rheum. 2006. PMID: 17133580 Free article.
Fcgamma receptors directly mediate cartilage, but not bone, destruction in murine antigen-induced arthritis: uncoupling of cartilage damage from bone erosion and joint inflammation.
van Lent PL, Grevers L, Lubberts E, de Vries TJ, Nabbe KC, Verbeek S, Oppers B, Sloetjes A, Blom AB, van den Berg WB. van Lent PL, et al. Among authors: nabbe kc. Arthritis Rheum. 2006 Dec;54(12):3868-77. doi: 10.1002/art.22253. Arthritis Rheum. 2006. PMID: 17133594 Free article.
Dendritic cells from patients with rheumatoid arthritis lack the interleukin 13 mediated increase of Fc gamma RII expression, which has clear functional consequences.
Radstake TR, Nabbe KC, Wenink MH, Roelofs MF, Oosterlaar A, van Lieshout AW, Barrera P, van Lent PL, van den Berg WB. Radstake TR, et al. Among authors: nabbe kc. Ann Rheum Dis. 2005 Dec;64(12):1737-43. doi: 10.1136/ard.2004.034405. Epub 2005 May 5. Ann Rheum Dis. 2005. PMID: 15878907 Free PMC article.
NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-gamma-stimulated immune complex arthritis.
van Lent PL, Nabbe KC, Blom AB, Sloetjes A, Holthuysen AE, Kolls J, Van De Loo FA, Holland SM, Van Den Berg WB. van Lent PL, et al. Among authors: nabbe kc. Arthritis Res Ther. 2005;7(4):R885-95. doi: 10.1186/ar1760. Epub 2005 May 20. Arthritis Res Ther. 2005. PMID: 15987491 Free PMC article.
The inhibitory receptor FcgammaRII reduces joint inflammation and destruction in experimental immune complex-mediated arthritides not only by inhibition of FcgammaRI/III but also by efficient clearance and endocytosis of immune complexes.
van Lent P, Nabbe KC, Boross P, Blom AB, Roth J, Holthuysen A, Sloetjes A, Verbeek S, van den Berg W. van Lent P, et al. Among authors: nabbe kc. Am J Pathol. 2003 Nov;163(5):1839-48. doi: 10.1016/s0002-9440(10)63543-2. Am J Pathol. 2003. PMID: 14578184 Free PMC article.
20 results