Sieber O - Search Results

1

Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.

Suraweera N, Haines J, McCart A, Rogers P, Latchford A, Coster M, Polanco-Echeverry G, Guenther T, Wang J, Sieber O, Tomlinson I, Silver A. Suraweera N, et al. Among authors: sieber o. Hum Mol Genet. 2006 Dec 1;15(23):3429-35. doi: 10.1093/hmg/ddl419. Epub 2006 Oct 24. Hum Mol Genet. 2006. PMID: 17062636

2

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q.

Lamlum H, Al Tassan N, Jaeger E, Frayling I, Sieber O, Reza FB, Eckert M, Rowan A, Barclay E, Atkin W, Williams C, Gilbert J, Cheadle J, Bell J, Houlston R, Bodmer W, Sampson J, Tomlinson I. Lamlum H, et al. Among authors: sieber o. Hum Mol Genet. 2000 Sep 22;9(15):2215-21. doi: 10.1093/oxfordjournals.hmg.a018912. Hum Mol Genet. 2000. PMID: 11001924

3

The adenomatous polyposis coli (APC) tumour suppressor--genetics, function and disease.

Sieber OM, Tomlinson IP, Lamlum H. Sieber OM, et al. Mol Med Today. 2000 Dec;6(12):462-9. doi: 10.1016/s1357-4310(00)01828-1. Mol Med Today. 2000. PMID: 11099951 Review.

4

Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas.

Sieber OM, Lamlum H, Crabtree MD, Rowan AJ, Barclay E, Lipton L, Hodgson S, Thomas HJ, Neale K, Phillips RK, Farrington SM, Dunlop MG, Mueller HJ, Bisgaard ML, Bulow S, Fidalgo P, Albuquerque C, Scarano MI, Bodmer W, Tomlinson IP, Heinimann K. Sieber OM, et al. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2954-8. doi: 10.1073/pnas.042699199. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867715 Free PMC article.

5

Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC.

Sieber OM, Heinimann K, Gorman P, Lamlum H, Crabtree M, Simpson CA, Davies D, Neale K, Hodgson SV, Roylance RR, Phillips RK, Bodmer WF, Tomlinson IP. Sieber OM, et al. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16910-5. doi: 10.1073/pnas.012679099. Epub 2002 Dec 16. Proc Natl Acad Sci U S A. 2002. PMID: 12486240 Free PMC article.

6

Colorectal tumourigenesis in carriers of the APC I1307K variant: lone gunman or conspiracy?

Sieber O, Lipton L, Heinimann K, Tomlinson I. Sieber O, et al. J Pathol. 2003 Feb;199(2):137-9. doi: 10.1002/path.1272. J Pathol. 2003. PMID: 12533824 Review.

7

Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.

Sieber OM, Lipton L, Crabtree M, Heinimann K, Fidalgo P, Phillips RK, Bisgaard ML, Orntoft TF, Aaltonen LA, Hodgson SV, Thomas HJ, Tomlinson IP. Sieber OM, et al. N Engl J Med. 2003 Feb 27;348(9):791-9. doi: 10.1056/NEJMoa025283. N Engl J Med. 2003. PMID: 12606733 Free article.

8

Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.

Halford SE, Rowan AJ, Lipton L, Sieber OM, Pack K, Thomas HJ, Hodgson SV, Bodmer WF, Tomlinson IP. Halford SE, et al. Am J Pathol. 2003 May;162(5):1545-8. doi: 10.1016/S0002-9440(10)64288-5. Am J Pathol. 2003. PMID: 12707038 Free PMC article.

9

Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients.

Crabtree M, Sieber OM, Lipton L, Hodgson SV, Lamlum H, Thomas HJ, Neale K, Phillips RK, Heinimann K, Tomlinson IP. Crabtree M, et al. Oncogene. 2003 Jul 3;22(27):4257-65. doi: 10.1038/sj.onc.1206471. Oncogene. 2003. PMID: 12833148

10

Genomic instability--the engine of tumorigenesis?

Sieber OM, Heinimann K, Tomlinson IP. Sieber OM, et al. Nat Rev Cancer. 2003 Sep;3(9):701-8. doi: 10.1038/nrc1170. Nat Rev Cancer. 2003. PMID: 12951589 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

152 results

Search Page

Filters