Fraser R - Search Results

1

Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.

Imrie H, Freel M, Mayosi BM, Davies E, Fraser R, Ingram M, Cordell HJ, Farrall M, Avery PJ, Watkins H, Keavney B, Connell JM. Imrie H, et al. Among authors: fraser r. J Clin Endocrinol Metab. 2006 Dec;91(12):5051-6. doi: 10.1210/jc.2006-1481. Epub 2006 Sep 19. J Clin Endocrinol Metab. 2006. PMID: 16984984

2

Variation at the aldosterone synthase (CYP11B2) locus contributes to hypertension in subjects with a raised aldosterone-to-renin ratio.

Lim PO, Macdonald TM, Holloway C, Friel E, Anderson NH, Dow E, Jung RT, Davies E, Fraser R, Connell JM. Lim PO, et al. Among authors: fraser r. J Clin Endocrinol Metab. 2002 Sep;87(9):4398-402. doi: 10.1210/jc.2001-012070. J Clin Endocrinol Metab. 2002. PMID: 12213905

3

Regulation of aldosterone synthase gene expression in the rat adrenal gland and central nervous system by sodium and angiotensin II.

Ye P, Kenyon CJ, MacKenzie SM, Seckl JR, Fraser R, Connell JM, Davies E. Ye P, et al. Among authors: fraser r. Endocrinology. 2003 Aug;144(8):3321-8. doi: 10.1210/en.2003-0109. Endocrinology. 2003. PMID: 12865309

4

Aldosterone synthase gene variation and adrenocortical response to sodium status, angiotensin II and ACTH in normal male subjects.

Kennon B, Ingram MC, Friel EC, Anderson NH, MacKenzie SM, Davies E, Shakerdi L, Wallace AM, Fraser R, Connell JM. Kennon B, et al. Among authors: fraser r. Clin Endocrinol (Oxf). 2004 Aug;61(2):174-81. doi: 10.1111/j.1365-2265.2004.02073.x. Clin Endocrinol (Oxf). 2004. PMID: 15272911 Clinical Trial.

5

Studies on the origin of circulating 18-hydroxycortisol and 18-oxocortisol in normal human subjects.

Freel EM, Shakerdi LA, Friel EC, Wallace AM, Davies E, Fraser R, Connell JM. Freel EM, et al. Among authors: fraser r. J Clin Endocrinol Metab. 2004 Sep;89(9):4628-33. doi: 10.1210/jc.2004-0379. J Clin Endocrinol Metab. 2004. PMID: 15356073 Free PMC article.

6

Genetic variation at the locus encompassing 11-beta hydroxylase and aldosterone synthase accounts for heritability in cortisol precursor (11-deoxycortisol) urinary metabolite excretion.

Keavney B, Mayosi B, Gaukrodger N, Imrie H, Baker M, Fraser R, Ingram M, Watkins H, Farrall M, Davies E, Connell J. Keavney B, et al. Among authors: fraser r. J Clin Endocrinol Metab. 2005 Feb;90(2):1072-7. doi: 10.1210/jc.2004-0870. Epub 2004 Nov 2. J Clin Endocrinol Metab. 2005. PMID: 15522937

7

Functional effects of genetic variants in the 11beta-hydroxylase (CYP11B1) gene.

Barr M, MacKenzie SM, Wilkinson DM, Holloway CD, Friel EC, Miller S, MacDonald T, Fraser R, Connell JM, Davies E. Barr M, et al. Among authors: fraser r. Clin Endocrinol (Oxf). 2006 Dec;65(6):816-25. doi: 10.1111/j.1365-2265.2006.02673.x. Clin Endocrinol (Oxf). 2006. PMID: 17121536

8

Effects of ACTH, dexamethasone, and adrenalectomy on 11beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) gene expression in the rat central nervous system.

Ye P, Kenyon CJ, Mackenzie SM, Nichol K, Seckl JR, Fraser R, Connell JM, Davies E. Ye P, et al. Among authors: fraser r. J Endocrinol. 2008 Feb;196(2):305-11. doi: 10.1677/JOE-07-0439. J Endocrinol. 2008. PMID: 18252953 Free PMC article.

9

Depot-specific steroidogenic gene transcription in human adipose tissue.

MacKenzie SM, Huda SS, Sattar N, Fraser R, Connell JM, Davies E. MacKenzie SM, et al. Among authors: fraser r. Clin Endocrinol (Oxf). 2008 Dec;69(6):848-54. doi: 10.1111/j.1365-2265.2008.03262.x. Epub 2008 Apr 10. Clin Endocrinol (Oxf). 2008. PMID: 18410552

10

Altered corticosteroid biosynthesis in essential hypertension: A digenic phenomenon.

Davies E, Mackenzie SM, Freel EM, Alvarez-Madrazo S, Fraser R, Connell JM. Davies E, et al. Among authors: fraser r. Mol Cell Endocrinol. 2009 Mar 5;300(1-2):185-91. doi: 10.1016/j.mce.2008.09.014. Epub 2008 Sep 19. Mol Cell Endocrinol. 2009. PMID: 18848600 Review.

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