Van Voorhis WC - Search Results

1

Structurally simple, potent, Plasmodium selective farnesyltransferase inhibitors that arrest the growth of malaria parasites.

Glenn MP, Chang SY, Hornéy C, Rivas K, Yokoyama K, Pusateri EE, Fletcher S, Cummings CG, Buckner FS, Pendyala PR, Chakrabarti D, Sebti SM, Gelb M, Van Voorhis WC, Hamilton AD. Glenn MP, et al. Among authors: van voorhis wc. J Med Chem. 2006 Sep 21;49(19):5710-27. doi: 10.1021/jm060081v. J Med Chem. 2006. PMID: 16970397 Free PMC article.

2

Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase.

Buckner FS, Verlinde CL, La Flamme AC, Van Voorhis WC. Buckner FS, et al. Among authors: van voorhis wc. Antimicrob Agents Chemother. 1996 Nov;40(11):2592-7. doi: 10.1128/AAC.40.11.2592. Antimicrob Agents Chemother. 1996. PMID: 8913471 Free PMC article.

3

Trypanosoma cruzi: use of herpes simplex virus-thymidine kinase as a negative selectable marker.

Buckner FS, Wilson AJ, Van Voorhis WC. Buckner FS, et al. Among authors: van voorhis wc. Exp Parasitol. 1997 Jul;86(3):171-80. doi: 10.1006/expr.1997.4163. Exp Parasitol. 1997. PMID: 9225767

4

Trypanosoma cruzi infection does not impair major histocompatibility complex class I presentation of antigen to cytotoxic T lymphocytes.

Buckner FS, Wipke BT, Van Voorhis WC. Buckner FS, et al. Among authors: van voorhis wc. Eur J Immunol. 1997 Oct;27(10):2541-8. doi: 10.1002/eji.1830271012. Eur J Immunol. 1997. PMID: 9368608

5

The effects of protein farnesyltransferase inhibitors on trypanosomatids: inhibition of protein farnesylation and cell growth.

Yokoyama K, Trobridge P, Buckner FS, Scholten J, Stuart KD, Van Voorhis WC, Gelb MH. Yokoyama K, et al. Among authors: van voorhis wc. Mol Biochem Parasitol. 1998 Jul 1;94(1):87-97. doi: 10.1016/s0166-6851(98)00053-x. Mol Biochem Parasitol. 1998. PMID: 9719512

6

Protein farnesyltransferase from Trypanosoma brucei. A heterodimer of 61- and 65-kda subunits as a new target for antiparasite therapeutics.

Yokoyama K, Trobridge P, Buckner FS, Van Voorhis WC, Stuart KD, Gelb MH. Yokoyama K, et al. Among authors: van voorhis wc. J Biol Chem. 1998 Oct 9;273(41):26497-505. doi: 10.1074/jbc.273.41.26497. J Biol Chem. 1998. PMID: 9756885 Free article.

7

Induction of resistance to azole drugs in Trypanosoma cruzi.

Buckner FS, Wilson AJ, White TC, Van Voorhis WC. Buckner FS, et al. Among authors: van voorhis wc. Antimicrob Agents Chemother. 1998 Dec;42(12):3245-50. doi: 10.1128/AAC.42.12.3245. Antimicrob Agents Chemother. 1998. PMID: 9835521 Free PMC article.

8

Detection of live Trypanosoma cruzi in tissues of infected mice by using histochemical stain for beta-galactosidase.

Buckner FS, Wilson AJ, Van Voorhis WC. Buckner FS, et al. Among authors: van voorhis wc. Infect Immun. 1999 Jan;67(1):403-9. doi: 10.1128/IAI.67.1.403-409.1999. Infect Immun. 1999. PMID: 9864242 Free PMC article.

9

Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase.

Aronov AM, Suresh S, Buckner FS, Van Voorhis WC, Verlinde CL, Opperdoes FR, Hol WG, Gelb MH. Aronov AM, et al. Among authors: van voorhis wc. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4273-8. doi: 10.1073/pnas.96.8.4273. Proc Natl Acad Sci U S A. 1999. PMID: 10200252 Free PMC article.

10

Cloning, heterologous expression, and distinct substrate specificity of protein farnesyltransferase from Trypanosoma brucei.

Buckner FS, Yokoyama K, Nguyen L, Grewal A, Erdjument-Bromage H, Tempst P, Strickland CL, Xiao L, Van Voorhis WC, Gelb MH. Buckner FS, et al. Among authors: van voorhis wc. J Biol Chem. 2000 Jul 21;275(29):21870-6. doi: 10.1074/jbc.M000975200. J Biol Chem. 2000. PMID: 10749864 Free PMC article.

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