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Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants.
Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K, Wakabayashi N, Katoh Y, Yamamoto M, Talalay P. Dinkova-Kostova AT, et al. Among authors: wakabayashi n. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11908-13. doi: 10.1073/pnas.172398899. Epub 2002 Aug 22. Proc Natl Acad Sci U S A. 2002. PMID: 12193649 Free PMC article.
393 results