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Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophages and distinct atherosclerosis at relatively low plasma cholesterol levels.
Out R, Hoekstra M, Habets K, Meurs I, de Waard V, Hildebrand RB, Wang Y, Chimini G, Kuiper J, Van Berkel TJ, Van Eck M. Out R, et al. Arterioscler Thromb Vasc Biol. 2008 Feb;28(2):258-64. doi: 10.1161/ATVBAHA.107.156935. Epub 2007 Nov 15. Arterioscler Thromb Vasc Biol. 2008. PMID: 18006857
Enhanced foam cell formation, atherosclerotic lesion development, and inflammation by combined deletion of ABCA1 and SR-BI in Bone marrow-derived cells in LDL receptor knockout mice on western-type diet.
Zhao Y, Pennings M, Hildebrand RB, Ye D, Calpe-Berdiel L, Out R, Kjerrulf M, Hurt-Camejo E, Groen AK, Hoekstra M, Jessup W, Chimini G, Van Berkel TJ, Van Eck M. Zhao Y, et al. Among authors: out r. Circ Res. 2010 Dec 10;107(12):e20-31. doi: 10.1161/CIRCRESAHA.110.226282. Epub 2010 Nov 11. Circ Res. 2010. PMID: 21071707
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