Roberts C - Search Results

1

Identification of potential pharmacological and toxicological targets differentiating structural analogs by a combination of transcriptional profiling and promoter analysis in LS-180 and Caco-2 adenocarcinoma cell lines.

Hartley DP, Dai X, Yabut J, Chu X, Cheng O, Zhang T, He YD, Roberts C, Ulrich R, Evers R, Evans DC. Hartley DP, et al. Among authors: roberts c. Pharmacogenet Genomics. 2006 Aug;16(8):579-99. doi: 10.1097/01.fpc.0000220561.59972.7a. Pharmacogenet Genomics. 2006. PMID: 16847427

2

Gene expression profiling of rat liver reveals a mechanistic basis for ritonavir-induced hyperlipidemia.

Lum PY, He YD, Slatter JG, Waring JF, Zelinsky N, Cavet G, Dai X, Fong O, Gum R, Jin L, Adamson GE, Roberts CJ, Olsen DB, Hazuda DJ, Ulrich RG. Lum PY, et al. Genomics. 2007 Oct;90(4):464-73. doi: 10.1016/j.ygeno.2007.06.004. Epub 2007 Aug 23. Genomics. 2007. PMID: 17719200 Free article.

3

Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: a resource for investigations into drug disposition.

Bleasby K, Castle JC, Roberts CJ, Cheng C, Bailey WJ, Sina JF, Kulkarni AV, Hafey MJ, Evers R, Johnson JM, Ulrich RG, Slatter JG. Bleasby K, et al. Among authors: roberts cj. Xenobiotica. 2006 Oct-Nov;36(10-11):963-88. doi: 10.1080/00498250600861751. Xenobiotica. 2006. PMID: 17118916

4

Development of an approach for ab initio estimation of compound-induced liver injury based on global gene transcriptional profiles.

Dai X, He YD, Dai H, Lum PY, Roberts CJ, Waring JF, Ulrich RG. Dai X, et al. Genome Inform. 2006;17(2):77-88. Genome Inform. 2006. PMID: 17503381

5

Profiling the hepatic effects of flutamide in rats: a microarray comparison with classical aryl hydrocarbon receptor ligands and atypical CYP1A inducers.

Coe KJ, Nelson SD, Ulrich RG, He Y, Dai X, Cheng O, Caguyong M, Roberts CJ, Slatter JG. Coe KJ, et al. Drug Metab Dispos. 2006 Jul;34(7):1266-75. doi: 10.1124/dmd.105.009159. Epub 2006 Apr 12. Drug Metab Dispos. 2006. PMID: 16611858

6

Microarray-based compendium of hepatic gene expression profiles for prototypical ADME gene-inducing compounds in rats and mice in vivo.

Slatter JG, Cheng O, Cornwell PD, de Souza A, Rockett J, Rushmore T, Hartley D, Evers R, He Y, Dai X, Hu R, Caguyong M, Roberts CJ, Castle J, Ulrich RG. Slatter JG, et al. Among authors: roberts cj. Xenobiotica. 2006 Oct-Nov;36(10-11):902-37. doi: 10.1080/00498250600861694. Xenobiotica. 2006. PMID: 17118914

7

Development of a DNA microarray for toxicology based on hepatotoxin-regulated sequences.

Waring JF, Cavet G, Jolly RA, McDowell J, Dai H, Ciurlionis R, Zhang C, Stoughton R, Lum P, Ferguson A, Roberts CJ, Ulrich RG. Waring JF, et al. Among authors: roberts cj. EHP Toxicogenomics. 2003 Jan;111(1T):53-60. EHP Toxicogenomics. 2003. PMID: 12735110

8

Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles.

Waring JF, Jolly RA, Ciurlionis R, Lum PY, Praestgaard JT, Morfitt DC, Buratto B, Roberts C, Schadt E, Ulrich RG. Waring JF, et al. Among authors: roberts c. Toxicol Appl Pharmacol. 2001 Aug 15;175(1):28-42. doi: 10.1006/taap.2001.9243. Toxicol Appl Pharmacol. 2001. PMID: 11509024

9

Chronic immune activation is a distinguishing feature of liver and PBMC gene signatures from HCV/HIV coinfected patients and may contribute to hepatic fibrogenesis.

Rasmussen AL, Wang IM, Shuhart MC, Proll SC, He Y, Cristescu R, Roberts C, Carter VS, Williams CM, Diamond DL, Bryan JT, Ulrich R, Korth MJ, Thomassen LV, Katze MG. Rasmussen AL, et al. Among authors: roberts c. Virology. 2012 Aug 15;430(1):43-52. doi: 10.1016/j.virol.2012.04.011. Epub 2012 May 16. Virology. 2012. PMID: 22608059 Free PMC article.

10

Functional discovery via a compendium of expression profiles.

Hughes TR, Marton MJ, Jones AR, Roberts CJ, Stoughton R, Armour CD, Bennett HA, Coffey E, Dai H, He YD, Kidd MJ, King AM, Meyer MR, Slade D, Lum PY, Stepaniants SB, Shoemaker DD, Gachotte D, Chakraburtty K, Simon J, Bard M, Friend SH. Hughes TR, et al. Among authors: roberts cj. Cell. 2000 Jul 7;102(1):109-26. doi: 10.1016/s0092-8674(00)00015-5. Cell. 2000. PMID: 10929718 Free article.

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