Hartley DP - Search Results

1

Identification of potential pharmacological and toxicological targets differentiating structural analogs by a combination of transcriptional profiling and promoter analysis in LS-180 and Caco-2 adenocarcinoma cell lines.

Hartley DP, Dai X, Yabut J, Chu X, Cheng O, Zhang T, He YD, Roberts C, Ulrich R, Evers R, Evans DC. Hartley DP, et al. Pharmacogenet Genomics. 2006 Aug;16(8):579-99. doi: 10.1097/01.fpc.0000220561.59972.7a. Pharmacogenet Genomics. 2006. PMID: 16847427

2

Activators of the rat pregnane X receptor differentially modulate hepatic and intestinal gene expression.

Hartley DP, Dai X, He YD, Carlini EJ, Wang B, Huskey SE, Ulrich RG, Rushmore TH, Evers R, Evans DC. Hartley DP, et al. Mol Pharmacol. 2004 May;65(5):1159-71. doi: 10.1124/mol.65.5.1159. Mol Pharmacol. 2004. PMID: 15102944

3

Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes.

Hariparsad N, Chu X, Yabut J, Labhart P, Hartley DP, Dai X, Evers R. Hariparsad N, et al. Among authors: hartley dp. Nucleic Acids Res. 2009 Mar;37(4):1160-73. doi: 10.1093/nar/gkn1047. Epub 2009 Jan 7. Nucleic Acids Res. 2009. PMID: 19129222 Free PMC article.

4

Attenuating pregnane X receptor (PXR) activation: a molecular modelling approach.

Gao YD, Olson SH, Balkovec JM, Zhu Y, Royo I, Yabut J, Evers R, Tan EY, Tang W, Hartley DP, Mosley RT. Gao YD, et al. Among authors: hartley dp. Xenobiotica. 2007 Feb;37(2):124-38. doi: 10.1080/00498250601050412. Xenobiotica. 2007. PMID: 17484516

5

Characterization of mice lacking the multidrug resistance protein MRP2 (ABCC2).

Chu XY, Strauss JR, Mariano MA, Li J, Newton DJ, Cai X, Wang RW, Yabut J, Hartley DP, Evans DC, Evers R. Chu XY, et al. Among authors: hartley dp. J Pharmacol Exp Ther. 2006 May;317(2):579-89. doi: 10.1124/jpet.105.098665. Epub 2006 Jan 18. J Pharmacol Exp Ther. 2006. PMID: 16421286

6

Microarray-based compendium of hepatic gene expression profiles for prototypical ADME gene-inducing compounds in rats and mice in vivo.

Slatter JG, Cheng O, Cornwell PD, de Souza A, Rockett J, Rushmore T, Hartley D, Evers R, He Y, Dai X, Hu R, Caguyong M, Roberts CJ, Castle J, Ulrich RG. Slatter JG, et al. Xenobiotica. 2006 Oct-Nov;36(10-11):902-37. doi: 10.1080/00498250600861694. Xenobiotica. 2006. PMID: 17118914

7

Induction of hepatic phase II drug-metabolizing enzymes by 1,7-phenanthroline in rats is accompanied by induction of MRP3.

Wang S, Hartley DP, Ciccotto SL, Vincent SH, Franklin RB, Kim MS. Wang S, et al. Among authors: hartley dp. Drug Metab Dispos. 2003 Jun;31(6):773-5. doi: 10.1124/dmd.31.6.773. Drug Metab Dispos. 2003. PMID: 12756211

8

Metallothionein-I/II knockout mice are sensitive to acetaminophen-induced hepatotoxicity.

Liu J, Liu Y, Hartley D, Klaassen CD, Shehin-Johnson SE, Lucas A, Cohen SD. Liu J, et al. J Pharmacol Exp Ther. 1999 Apr;289(1):580-6. J Pharmacol Exp Ther. 1999. PMID: 10087053

9

Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats.

Cherrington NJ, Hartley DP, Li N, Johnson DR, Klaassen CD. Cherrington NJ, et al. Among authors: hartley dp. J Pharmacol Exp Ther. 2002 Jan;300(1):97-104. doi: 10.1124/jpet.300.1.97. J Pharmacol Exp Ther. 2002. PMID: 11752103

10

Gender-specific and developmental influences on the expression of rat organic anion transporters.

Buist SC, Cherrington NJ, Choudhuri S, Hartley DP, Klaassen CD. Buist SC, et al. Among authors: hartley dp. J Pharmacol Exp Ther. 2002 Apr;301(1):145-51. doi: 10.1124/jpet.301.1.145. J Pharmacol Exp Ther. 2002. PMID: 11907168

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