Hickman JA - Search Results

1

Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells.

Maubant S, Saint-Dizier D, Boutillon M, Perron-Sierra F, Casara PJ, Hickman JA, Tucker GC, Van Obberghen-Schilling E. Maubant S, et al. Among authors: hickman ja. Blood. 2006 Nov 1;108(9):3035-44. doi: 10.1182/blood-2006-05-023580. Epub 2006 Jul 11. Blood. 2006. PMID: 16835373 Free article.

2

Decrease in survival threshold of quiescent colon carcinoma cells in the presence of a small molecule integrin antagonist.

Burbridge MF, Venot V, Casara PJ, Perron-Sierra F, Hickman JA, Tucker GC. Burbridge MF, et al. Among authors: hickman ja. Mol Pharmacol. 2003 Jun;63(6):1281-8. doi: 10.1124/mol.63.6.1281. Mol Pharmacol. 2003. PMID: 12761337

3

Synthesis of N,N'-disubstituted 3-aminobenzo[c] and [d]azepin-2-ones as potent and specific farnesyl transferase inhibitors.

Le Diguarher T, Ortuno JC, Shanks D, Guilbaud N, Pierré A, Raimbaud E, Fauchère JL, Hickman JA, Tucker GC, Casara PJ. Le Diguarher T, et al. Among authors: hickman ja. Bioorg Med Chem Lett. 2004 Feb 9;14(3):767-71. doi: 10.1016/j.bmcl.2003.11.013. Bioorg Med Chem Lett. 2004. PMID: 14741286

4

Bax activation by engagement with, then release from, the BH3 binding site of Bcl-xL.

Gautier F, Guillemin Y, Cartron PF, Gallenne T, Cauquil N, Le Diguarher T, Casara P, Vallette FM, Manon S, Hickman JA, Geneste O, Juin P. Gautier F, et al. Among authors: hickman ja. Mol Cell Biol. 2011 Feb;31(4):832-44. doi: 10.1128/MCB.00161-10. Epub 2010 Dec 20. Mol Cell Biol. 2011. PMID: 21173168 Free PMC article.

5

Parallel liquid synthesis of N,N'-Disubstituted 3-amino azepin-2-ones as potent and specific farnesyl transferase inhibitors.

Le Diguarher T, Ortuno JC, Dorey G, Shanks D, Guilbaud N, Pierré A, Fauchère JL, Hickman JA, Tucker GC, Casara PJ. Le Diguarher T, et al. Among authors: hickman ja. Bioorg Med Chem. 2003 Jul 17;11(14):3193-204. doi: 10.1016/s0968-0896(03)00218-9. Bioorg Med Chem. 2003. PMID: 12818682

6

Controlled exploration of structural databases: the case of farnesyl transferase inhibitors.

Tizot A, Tucker GC, Pierré A, Hickman J, Goldstein S. Tizot A, et al. Med Chem. 2009 May;5(3):208-15. doi: 10.2174/157340609788185891. Med Chem. 2009. PMID: 19442210

7

S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.

Casara P, Davidson J, Claperon A, Le Toumelin-Braizat G, Vogler M, Bruno A, Chanrion M, Lysiak-Auvity G, Le Diguarher T, Starck JB, Chen I, Whitehead N, Graham C, Matassova N, Dokurno P, Pedder C, Wang Y, Qiu S, Girard AM, Schneider E, Gravé F, Studeny A, Guasconi G, Rocchetti F, Maïga S, Henlin JM, Colland F, Kraus-Berthier L, Le Gouill S, Dyer MJS, Hubbard R, Wood M, Amiot M, Cohen GM, Hickman JA, Morris E, Murray J, Geneste O. Casara P, et al. Among authors: hickman ja. Oncotarget. 2018 Apr 13;9(28):20075-20088. doi: 10.18632/oncotarget.24744. eCollection 2018 Apr 13. Oncotarget. 2018. PMID: 29732004 Free PMC article.

8

Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells.

Marty B, Maire V, Gravier E, Rigaill G, Vincent-Salomon A, Kappler M, Lebigot I, Djelti F, Tourdès A, Gestraud P, Hupé P, Barillot E, Cruzalegui F, Tucker GC, Stern MH, Thiery JP, Hickman JA, Dubois T. Marty B, et al. Among authors: hickman ja. Breast Cancer Res. 2008;10(6):R101. doi: 10.1186/bcr2204. Epub 2008 Dec 3. Breast Cancer Res. 2008. PMID: 19055754 Free PMC article.

9

Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.

Murray JB, Davidson J, Chen I, Davis B, Dokurno P, Graham CJ, Harris R, Jordan A, Matassova N, Pedder C, Ray S, Roughley SD, Smith J, Walmsley C, Wang Y, Whitehead N, Williamson DS, Casara P, Le Diguarher T, Hickman J, Stark J, Kotschy A, Geneste O, Hubbard RE. Murray JB, et al. ACS Omega. 2019 May 23;4(5):8892-8906. doi: 10.1021/acsomega.9b00611. eCollection 2019 May 31. ACS Omega. 2019. PMID: 31459977 Free PMC article.

10

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members.

Gallenne T, Gautier F, Oliver L, Hervouet E, Noël B, Hickman JA, Geneste O, Cartron PF, Vallette FM, Manon S, Juin P. Gallenne T, et al. Among authors: hickman ja. J Cell Biol. 2009 Apr 20;185(2):279-90. doi: 10.1083/jcb.200809153. J Cell Biol. 2009. PMID: 19380879 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

211 results

Search Page

Filters