Valente S - Search Results

1

3-(1H-pyrrol-2-yl)-2-oxazolidinones as novel monoamine oxidase type A inhibitors.

Mai A, Artico M, Valente S, Sbardella G, Turini P, Befani O, Vedova LD, Agostinelli E. Mai A, et al. Among authors: valente s. Med Chem. 2005 Mar;1(2):117-24. doi: 10.2174/1573406053175247. Med Chem. 2005. PMID: 16787307

2

3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity.

Mai A, Massa S, Cerbara I, Valente S, Ragno R, Bottoni P, Scatena R, Loidl P, Brosch G. Mai A, et al. Among authors: valente s. J Med Chem. 2004 Feb 26;47(5):1098-109. doi: 10.1021/jm030990+. J Med Chem. 2004. PMID: 14971890

3

3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies.

Ragno R, Mai A, Massa S, Cerbara I, Valente S, Bottoni P, Scatena R, Jesacher F, Loidl P, Brosch G. Ragno R, et al. Among authors: valente s. J Med Chem. 2004 Mar 11;47(6):1351-9. doi: 10.1021/jm031036f. J Med Chem. 2004. PMID: 14998325

4

Histone deacetylation in epigenetics: an attractive target for anticancer therapy.

Mai A, Massa S, Rotili D, Cerbara I, Valente S, Pezzi R, Simeoni S, Ragno R. Mai A, et al. Among authors: valente s. Med Res Rev. 2005 May;25(3):261-309. doi: 10.1002/med.20024. Med Res Rev. 2005. PMID: 15717297 Review.

5

3-D QSAR studies on histone deacetylase inhibitors. A GOLPE/GRID approach on different series of compounds.

Ragno R, Simeoni S, Valente S, Massa S, Mai A. Ragno R, et al. Among authors: valente s. J Chem Inf Model. 2006 May-Jun;46(3):1420-30. doi: 10.1021/ci050556b. J Chem Inf Model. 2006. PMID: 16711762

6

Synthesis and biological evaluation of 2-, 3-, and 4-acylaminocinnamyl-N-hydroxyamides as novel synthetic HDAC inhibitors.

Mai A, Massa S, Pezzi R, Valente S, Loidl P, Brosch G. Mai A, et al. Among authors: valente s. Med Chem. 2005 May;1(3):245-54. doi: 10.2174/1573406053765431. Med Chem. 2005. PMID: 16787320

7

Aroyl-pyrrolyl hydroxyamides: influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition.

Mai A, Massa S, Valente S, Simeoni S, Ragno R, Bottoni P, Scatena R, Brosch G. Mai A, et al. Among authors: valente s. ChemMedChem. 2006 Feb;1(2):225-37. doi: 10.1002/cmdc.200500015. ChemMedChem. 2006. PMID: 16892355

8

Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors.

Mai A, Valente S, Cheng D, Perrone A, Ragno R, Simeoni S, Sbardella G, Brosch G, Nebbioso A, Conte M, Altucci L, Bedford MT. Mai A, et al. Among authors: valente s. ChemMedChem. 2007 Jul;2(7):987-91. doi: 10.1002/cmdc.200700023. ChemMedChem. 2007. PMID: 17458842 No abstract available.

9

Novel pyrrole-containing histone deacetylase inhibitors endowed with cytodifferentiation activity.

Mai A, Valente S, Rotili D, Massa S, Botta G, Brosch G, Miceli M, Nebbioso A, Altucci L. Mai A, et al. Among authors: valente s. Int J Biochem Cell Biol. 2007;39(7-8):1510-22. doi: 10.1016/j.biocel.2007.03.020. Epub 2007 Apr 4. Int J Biochem Cell Biol. 2007. PMID: 17482499

10

Identification of two new synthetic histone deacetylase inhibitors that modulate globin gene expression in erythroid cells from healthy donors and patients with thalassemia.

Mai A, Jelicic K, Rotili D, Di Noia A, Alfani E, Valente S, Altucci L, Nebbioso A, Massa S, Galanello R, Brosch G, Migliaccio AR, Migliaccio G. Mai A, et al. Among authors: valente s. Mol Pharmacol. 2007 Nov;72(5):1111-23. doi: 10.1124/mol.107.036772. Epub 2007 Jul 31. Mol Pharmacol. 2007. PMID: 17666592

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