Mitchell MJ - Search Results

1

PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase.

Luciani JJ, Depetris D, Usson Y, Metzler-Guillemain C, Mignon-Ravix C, Mitchell MJ, Megarbane A, Sarda P, Sirma H, Moncla A, Feunteun J, Mattei MG. Luciani JJ, et al. Among authors: mitchell mj. J Cell Sci. 2006 Jun 15;119(Pt 12):2518-31. doi: 10.1242/jcs.02965. Epub 2006 May 30. J Cell Sci. 2006. PMID: 16735446

2

Spermatozoa in mice lacking the nucleoporin NUP210L show defects in head shape and motility but not in nuclear compaction or histone replacement.

Al Dala Ali M, Longepied G, Nicolet A, Metzler-Guillemain C, Mitchell MJ. Al Dala Ali M, et al. Among authors: mitchell mj. Clin Genet. 2024 Apr;105(4):364-375. doi: 10.1111/cge.14468. Epub 2023 Dec 21. Clin Genet. 2024. PMID: 38129135

3

Spermatogenesis and the mouse Y chromosome: specialisation out of decay.

Mitchell MJ. Mitchell MJ. Results Probl Cell Differ. 2000;28:233-70. doi: 10.1007/978-3-540-48461-5_10. Results Probl Cell Differ. 2000. PMID: 10626301 Review. No abstract available.

4

Optimization of the activity and biodegradability of ionizable lipids for mRNA delivery via directed chemical evolution.

Han X, Alameh MG, Xu Y, Palanki R, El-Mayta R, Dwivedi G, Swingle KL, Xu J, Gong N, Xue L, Shi Q, Yoon IC, Warzecha CC, Wilson JM, Weissman D, Mitchell MJ. Han X, et al. Among authors: mitchell mj. Nat Biomed Eng. 2024 Nov;8(11):1412-1424. doi: 10.1038/s41551-024-01267-7. Epub 2024 Nov 22. Nat Biomed Eng. 2024. PMID: 39578640

5

Towards the clinical translation of a silver sulfide nanoparticle contrast agent: large scale production with a highly parallelized microfluidic chip.

Mossburg KJ, Shepherd SJ, Barragan D, O NH, Berkow EK, Maidment PSN, Rosario Berrios DN, Hsu JC, Siedlik MJ, Yadavali S, Mitchell MJ, Issadore D, Cormode DP. Mossburg KJ, et al. Among authors: mitchell mj. Eur J Nucl Med Mol Imaging. 2024 Nov 12. doi: 10.1007/s00259-024-06967-5. Online ahead of print. Eur J Nucl Med Mol Imaging. 2024. PMID: 39528844

6

Piperazine-derived bisphosphonate-based ionizable lipid nanoparticles enhance mRNA delivery to the bone microenvironment.

Mitchell MJ, Yoon IC, Xue L, Chen Q, Liu J, Xu J, Siddiqui Z, Kim D, Chen B, Shi Q, Han E, Ruiz M, Vining K. Mitchell MJ, et al. Angew Chem Int Ed Engl. 2024 Oct 8:e202415389. doi: 10.1002/anie.202415389. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39379320

7

Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery.

Xue L, Zhao G, Gong N, Han X, Shepherd SJ, Xiong X, Xiao Z, Palanki R, Xu J, Swingle KL, Warzecha CC, El-Mayta R, Chowdhary V, Yoon IC, Xu J, Cui J, Shi Y, Alameh MG, Wang K, Wang L, Pochan DJ, Weissman D, Vaughan AE, Wilson JM, Mitchell MJ. Xue L, et al. Among authors: mitchell mj. Nat Nanotechnol. 2024 Oct 1. doi: 10.1038/s41565-024-01747-6. Online ahead of print. Nat Nanotechnol. 2024. PMID: 39354147

8

Breaking the final barrier: Evolution of cationic and ionizable lipid structure in lipid nanoparticles to escape the endosome.

Mrksich K, Padilla MS, Mitchell MJ. Mrksich K, et al. Among authors: mitchell mj. Adv Drug Deliv Rev. 2024 Nov;214:115446. doi: 10.1016/j.addr.2024.115446. Epub 2024 Sep 16. Adv Drug Deliv Rev. 2024. PMID: 39293650 Review.

9

Lipid nanoparticle-mediated RNA delivery for immune cell modulation.

Kim EH, Teerdhala SV, Padilla MS, Joseph RA, Li JJ, Haley RM, Mitchell MJ. Kim EH, et al. Among authors: mitchell mj. Eur J Immunol. 2024 Sep 16:e2451008. doi: 10.1002/eji.202451008. Online ahead of print. Eur J Immunol. 2024. PMID: 39279550 Review.

10

Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery.

Gong N, Zhong W, Alameh MG, Han X, Xue L, El-Mayta R, Zhao G, Vaughan AE, Qin Z, Xu F, Hamilton AG, Kim D, Xu J, Kim J, Teng X, Li J, Liang XJ, Weissman D, Guo W, Mitchell MJ. Gong N, et al. Among authors: mitchell mj. Nat Mater. 2024 Dec;23(12):1736-1747. doi: 10.1038/s41563-024-01961-6. Epub 2024 Sep 2. Nat Mater. 2024. PMID: 39223270

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