Gaedigk R - Search Results

1

Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism.

Gaedigk A, Blum M, Gaedigk R, Eichelbaum M, Meyer UA. Gaedigk A, et al. Among authors: gaedigk r. Am J Hum Genet. 1991 May;48(5):943-50. Am J Hum Genet. 1991. PMID: 1673290 Free PMC article.

2

Discovery of a novel nonfunctional cytochrome P450 2D6 allele, CYP2D642, in African American subjects.

Gaedigk A, Ndjountché L, Gaedigk R, Leeder JS, Bradford LD. Gaedigk A, et al. Among authors: gaedigk r. Clin Pharmacol Ther. 2003 Jun;73(6):575-6. doi: 10.1016/S0009-9236(03)00067-5. Clin Pharmacol Ther. 2003. PMID: 12811367 No abstract available.

3

Genetic Heterogeneity in the rRNA Gene Locus of Trichophyton tonsurans.

Gaedigk A, Gaedigk R, Abdel-Rahman SM. Gaedigk A, et al. Among authors: gaedigk r. J Clin Microbiol. 2003 Dec;41(12):5478-87. doi: 10.1128/JCM.41.12.5478-5487.2003. J Clin Microbiol. 2003. PMID: 14662928 Free PMC article.

4

Variability of CYP3A7 expression in human fetal liver.

Leeder JS, Gaedigk R, Marcucci KA, Gaedigk A, Vyhlidal CA, Schindel BP, Pearce RE. Leeder JS, et al. Among authors: gaedigk a, gaedigk r. J Pharmacol Exp Ther. 2005 Aug;314(2):626-35. doi: 10.1124/jpet.105.086504. Epub 2005 Apr 21. J Pharmacol Exp Ther. 2005. PMID: 15845858 Free article.

5

CYP2D7 splice variants in human liver and brain: does CYP2D7 encode functional protein?

Gaedigk A, Gaedigk R, Leeder JS. Gaedigk A, et al. Among authors: gaedigk r. Biochem Biophys Res Commun. 2005 Nov 4;336(4):1241-50. doi: 10.1016/j.bbrc.2005.08.255. Biochem Biophys Res Commun. 2005. PMID: 16169517

6

Variability of CYP2J2 expression in human fetal tissues.

Gaedigk A, Baker DW, Totah RA, Gaedigk R, Pearce RE, Vyhlidal CA, Zeldin DC, Leeder JS. Gaedigk A, et al. Among authors: gaedigk r. J Pharmacol Exp Ther. 2006 Nov;319(2):523-32. doi: 10.1124/jpet.106.109215. Epub 2006 Jul 25. J Pharmacol Exp Ther. 2006. PMID: 16868033 Free PMC article.

7

UGT2B17 and SULT1A1 gene copy number variation (CNV) detection by LabChip microfluidic technology.

Gaedigk A, Gaedigk R, Leeder JS. Gaedigk A, et al. Among authors: gaedigk r. Clin Chem Lab Med. 2010 May;48(5):627-33. doi: 10.1515/CCLM.2010.128. Clin Chem Lab Med. 2010. PMID: 20192879

8

High-resolution melt analysis to detect sequence variations in highly homologous gene regions: application to CYP2B6.

Twist GP, Gaedigk R, Leeder JS, Gaedigk A. Twist GP, et al. Among authors: gaedigk a, gaedigk r. Pharmacogenomics. 2013 Jun;14(8):913-22. doi: 10.2217/pgs.13.66. Pharmacogenomics. 2013. PMID: 23746185 Free PMC article.

9

Age-Related Changes in MicroRNA Expression and Pharmacogenes in Human Liver.

Burgess KS, Philips S, Benson EA, Desta Z, Gaedigk A, Gaedigk R, Segar MW, Liu Y, Skaar TC. Burgess KS, et al. Among authors: gaedigk a, gaedigk r. Clin Pharmacol Ther. 2015 Aug;98(2):205-15. doi: 10.1002/cpt.145. Clin Pharmacol Ther. 2015. PMID: 25968989 Free PMC article.

10

Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation.

Pearce RE, Gaedigk R, Twist GP, Dai H, Riffel AK, Leeder JS, Gaedigk A. Pearce RE, et al. Among authors: gaedigk a, gaedigk r. Drug Metab Dispos. 2016 Jul;44(7):948-58. doi: 10.1124/dmd.115.067546. Epub 2015 Nov 25. Drug Metab Dispos. 2016. PMID: 26608082 Free PMC article.

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