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Heparan sulphate proteoglycans are essential for the myeloma cell growth activity of EGF-family ligands in multiple myeloma.
Mahtouk K, Cremer FW, Rème T, Jourdan M, Baudard M, Moreaux J, Requirand G, Fiol G, De Vos J, Moos M, Quittet P, Goldschmidt H, Rossi JF, Hose D, Klein B. Mahtouk K, et al. Among authors: baudard m. Oncogene. 2006 Nov 16;25(54):7180-91. doi: 10.1038/sj.onc.1209699. Epub 2006 May 29. Oncogene. 2006. PMID: 16732320 Free PMC article.
Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma.
Mahtouk K, Hose D, Raynaud P, Hundemer M, Jourdan M, Jourdan E, Pantesco V, Baudard M, De Vos J, Larroque M, Moehler T, Rossi JF, Rème T, Goldschmidt H, Klein B. Mahtouk K, et al. Among authors: baudard m. Blood. 2007 Jun 1;109(11):4914-23. doi: 10.1182/blood-2006-08-043232. Epub 2007 Mar 5. Blood. 2007. PMID: 17339423 Free PMC article.
28 results