Schiffer HH - Search Results

1

Integrative functional assays, chemical genomics and high throughput screening: harnessing signal transduction pathways to a common HTS readout.

Burstein ES, Piu F, Ma JN, Weissman JT, Currier EA, Nash NR, Weiner DM, Spalding TA, Schiffer HH, Del Tredici AL, Brann MR. Burstein ES, et al. Among authors: schiffer hh. Curr Pharm Des. 2006;12(14):1717-29. doi: 10.2174/138161206776873662. Curr Pharm Des. 2006. PMID: 16712484

2

Identification of the atypical L-type Ca2+ channel blocker diltiazem and its metabolites as ghrelin receptor agonists.

Ma JN, Schiffer HH, Knapp AE, Wang J, Wong KK, Currier EA, Owens M, Nash NR, Gardell LR, Brann MR, Olsson R, Burstein ES. Ma JN, et al. Among authors: schiffer hh. Mol Pharmacol. 2007 Aug;72(2):380-6. doi: 10.1124/mol.107.034298. Epub 2007 May 2. Mol Pharmacol. 2007. PMID: 17475811

3

Pharmacology of polymorphic variants of the human 5-HT1A receptor.

Del Tredici AL, Schiffer HH, Burstein ES, Lameh J, Mohell N, Hacksell U, Brann MR, Weiner DM. Del Tredici AL, et al. Among authors: schiffer hh. Biochem Pharmacol. 2004 Feb 1;67(3):479-90. doi: 10.1016/j.bcp.2003.09.030. Biochem Pharmacol. 2004. PMID: 15037200

4

Characterization of the Mas-related gene family: structural and functional conservation of human and rhesus MrgX receptors.

Burstein ES, Ott TR, Feddock M, Ma JN, Fuhs S, Wong S, Schiffer HH, Brann MR, Nash NR. Burstein ES, et al. Among authors: schiffer hh. Br J Pharmacol. 2006 Jan;147(1):73-82. doi: 10.1038/sj.bjp.0706448. Br J Pharmacol. 2006. PMID: 16284629 Free PMC article.

5

Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist.

Vanover KE, Weiner DM, Makhay M, Veinbergs I, Gardell LR, Lameh J, Del Tredici AL, Piu F, Schiffer HH, Ott TR, Burstein ES, Uldam AK, Thygesen MB, Schlienger N, Andersson CM, Son TY, Harvey SC, Powell SB, Geyer MA, Tolf BR, Brann MR, Davis RE. Vanover KE, et al. Among authors: schiffer hh. J Pharmacol Exp Ther. 2006 May;317(2):910-8. doi: 10.1124/jpet.105.097006. Epub 2006 Feb 9. J Pharmacol Exp Ther. 2006. PMID: 16469866

6

Pharmacology and signaling properties of epidermal growth factor receptor isoforms studied by bioluminescence resonance energy transfer.

Schiffer HH, Reding EC, Fuhs SR, Lu Q, Piu F, Wong S, Littler PL, Weiner DM, Keefe W, Tan PK, Nash NR, Knapp AE, Olsson R, Brann MR. Schiffer HH, et al. Mol Pharmacol. 2007 Feb;71(2):508-18. doi: 10.1124/mol.106.027656. Epub 2006 Sep 12. Mol Pharmacol. 2007. PMID: 16968809

7

Monitoring interactions between receptor tyrosine kinases and their downstream effector proteins in living cells using bioluminescence resonance energy transfer.

Tan PK, Wang J, Littler PL, Wong KK, Sweetnam TA, Keefe W, Nash NR, Reding EC, Piu F, Brann MR, Schiffer HH. Tan PK, et al. Among authors: schiffer hh. Mol Pharmacol. 2007 Dec;72(6):1440-6. doi: 10.1124/mol.107.039636. Epub 2007 Aug 22. Mol Pharmacol. 2007. PMID: 17715395

8

Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist.

Piu F, Cheevers C, Hyldtoft L, Gardell LR, Del Tredici AL, Andersen CB, Fairbairn LC, Lund BW, Gustafsson M, Schiffer HH, Donello JE, Olsson R, Gil DW, Brann MR. Piu F, et al. Among authors: schiffer hh. Eur J Pharmacol. 2008 Aug 20;590(1-3):423-9. doi: 10.1016/j.ejphar.2008.05.015. Epub 2008 May 23. Eur J Pharmacol. 2008. PMID: 18559275

9

Identification and characterization of novel small-molecule protease-activated receptor 2 agonists.

Gardell LR, Ma JN, Seitzberg JG, Knapp AE, Schiffer HH, Tabatabaei A, Davis CN, Owens M, Clemons B, Wong KK, Lund B, Nash NR, Gao Y, Lameh J, Schmelzer K, Olsson R, Burstein ES. Gardell LR, et al. Among authors: schiffer hh. J Pharmacol Exp Ther. 2008 Dec;327(3):799-808. doi: 10.1124/jpet.108.142570. Epub 2008 Sep 3. J Pharmacol Exp Ther. 2008. PMID: 18768780

10

AC-260584, an orally bioavailable M(1) muscarinic receptor allosteric agonist, improves cognitive performance in an animal model.

Bradley SR, Lameh J, Ohrmund L, Son T, Bajpai A, Nguyen D, Friberg M, Burstein ES, Spalding TA, Ott TR, Schiffer HH, Tabatabaei A, McFarland K, Davis RE, Bonhaus DW. Bradley SR, et al. Among authors: schiffer hh. Neuropharmacology. 2010 Feb;58(2):365-73. doi: 10.1016/j.neuropharm.2009.10.003. Epub 2009 Oct 14. Neuropharmacology. 2010. PMID: 19835892

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