Ma JN - Search Results

1

Integrative functional assays, chemical genomics and high throughput screening: harnessing signal transduction pathways to a common HTS readout.

Burstein ES, Piu F, Ma JN, Weissman JT, Currier EA, Nash NR, Weiner DM, Spalding TA, Schiffer HH, Del Tredici AL, Brann MR. Burstein ES, et al. Among authors: ma jn. Curr Pharm Des. 2006;12(14):1717-29. doi: 10.2174/138161206776873662. Curr Pharm Des. 2006. PMID: 16712484

2

Identification of the atypical L-type Ca2+ channel blocker diltiazem and its metabolites as ghrelin receptor agonists.

Ma JN, Schiffer HH, Knapp AE, Wang J, Wong KK, Currier EA, Owens M, Nash NR, Gardell LR, Brann MR, Olsson R, Burstein ES. Ma JN, et al. Mol Pharmacol. 2007 Aug;72(2):380-6. doi: 10.1124/mol.107.034298. Epub 2007 May 2. Mol Pharmacol. 2007. PMID: 17475811

3

Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954).

Croston GE, Olsson R, Currier EA, Burstein ES, Weiner D, Nash N, Severance D, Allenmark SG, Thunberg L, Ma JN, Mohell N, O'Dowd B, Brann MR, Hacksell U. Croston GE, et al. Among authors: ma jn. J Med Chem. 2002 Nov 7;45(23):4950-3. doi: 10.1021/jm025551+. J Med Chem. 2002. PMID: 12408704

4

G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway.

Weissman JT, Ma JN, Essex A, Gao Y, Burstein ES. Weissman JT, et al. Among authors: ma jn. Oncogene. 2004 Jan 8;23(1):241-9. doi: 10.1038/sj.onc.1207014. Oncogene. 2004. PMID: 14712229

5

Discovery of novel peptide/receptor interactions: identification of PHM-27 as a potent agonist of the human calcitonin receptor.

Ma JN, Currier EA, Essex A, Feddock M, Spalding TA, Nash NR, Brann MR, Burstein ES. Ma JN, et al. Biochem Pharmacol. 2004 Apr 1;67(7):1279-84. doi: 10.1016/j.bcp.2003.11.008. Biochem Pharmacol. 2004. PMID: 15013843

6

Characterization of the Mas-related gene family: structural and functional conservation of human and rhesus MrgX receptors.

Burstein ES, Ott TR, Feddock M, Ma JN, Fuhs S, Wong S, Schiffer HH, Brann MR, Nash NR. Burstein ES, et al. Among authors: ma jn. Br J Pharmacol. 2006 Jan;147(1):73-82. doi: 10.1038/sj.bjp.0706448. Br J Pharmacol. 2006. PMID: 16284629 Free PMC article.

7

Discovery of non-peptidergic MrgX1 and MrgX2 receptor agonists and exploration of an initial SAR using solid-phase synthesis.

Malik L, Kelly NM, Ma JN, Currier EA, Burstein ES, Olsson R. Malik L, et al. Among authors: ma jn. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1729-32. doi: 10.1016/j.bmcl.2009.01.085. Epub 2009 Jan 30. Bioorg Med Chem Lett. 2009. PMID: 19230660

8

Identification of the antiarrhythmic drugs amiodarone and lorcainide as potent H3 histamine receptor inverse agonists.

Del Tredici AL, Ma JN, Piu F, Burstein ES. Del Tredici AL, et al. Among authors: ma jn. J Pharmacol Exp Ther. 2014 Jan;348(1):116-24. doi: 10.1124/jpet.113.208892. Epub 2013 Nov 7. J Pharmacol Exp Ther. 2014. PMID: 24204014

9

Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist.

Burstein ES, Ma J, Wong S, Gao Y, Pham E, Knapp AE, Nash NR, Olsson R, Davis RE, Hacksell U, Weiner DM, Brann MR. Burstein ES, et al. J Pharmacol Exp Ther. 2005 Dec;315(3):1278-87. doi: 10.1124/jpet.105.092155. Epub 2005 Aug 31. J Pharmacol Exp Ther. 2005. PMID: 16135699

10

Structural requirements of transmembrane domain 3 for activation by the M1 muscarinic receptor agonists AC-42, AC-260584, clozapine, and N-desmethylclozapine: evidence for three distinct modes of receptor activation.

Spalding TA, Ma JN, Ott TR, Friberg M, Bajpai A, Bradley SR, Davis RE, Brann MR, Burstein ES. Spalding TA, et al. Among authors: ma jn. Mol Pharmacol. 2006 Dec;70(6):1974-83. doi: 10.1124/mol.106.024901. Epub 2006 Sep 7. Mol Pharmacol. 2006. PMID: 16959945

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