Zlotos DP - Search Results

1

Pharmacological characterisation of strychnine and brucine analogues at glycine and alpha7 nicotinic acetylcholine receptors.

Jensen AA, Gharagozloo P, Birdsall NJ, Zlotos DP. Jensen AA, et al. Among authors: zlotos dp. Eur J Pharmacol. 2006 Jun 6;539(1-2):27-33. doi: 10.1016/j.ejphar.2006.04.010. Epub 2006 May 9. Eur J Pharmacol. 2006. PMID: 16687139

2

Pharmacological characteristics and binding modes of caracurine V analogues and related compounds at the neuronal alpha7 nicotinic acetylcholine receptor.

Jensen AA, Zlotos DP, Liljefors T. Jensen AA, et al. Among authors: zlotos dp. J Med Chem. 2007 Sep 20;50(19):4616-29. doi: 10.1021/jm070574f. Epub 2007 Aug 28. J Med Chem. 2007. PMID: 17722904

3

Structure-activity relationships of strychnine analogs at glycine receptors.

Mohsen AM, Heller E, Holzgrabe U, Jensen AA, Zlotos DP. Mohsen AM, et al. Among authors: zlotos dp. Chem Biodivers. 2014 Aug;11(8):1256-62. doi: 10.1002/cbdv.201400110. Chem Biodivers. 2014. PMID: 25146769

4

Semisynthetic analogues of toxiferine I and their pharmacological properties at α7 nAChRs, muscle-type nAChRs, and the allosteric binding site of muscarinic M2 receptors.

Zlotos DP, Tränkle C, Holzgrabe U, Gündisch D, Jensen AA. Zlotos DP, et al. J Nat Prod. 2014 Sep 26;77(9):2006-13. doi: 10.1021/np500259j. Epub 2014 Sep 5. J Nat Prod. 2014. PMID: 25192059 Free PMC article.

5

Oxime Ethers of (E)-11-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists.

Mohsen AM, Mandour YM, Sarukhanyan E, Breitinger U, Villmann C, Banoub MM, Breitinger HG, Dandekar T, Holzgrabe U, Sotriffer C, Jensen AA, Zlotos DP. Mohsen AM, et al. Among authors: zlotos dp. J Nat Prod. 2016 Dec 23;79(12):2997-3005. doi: 10.1021/acs.jnatprod.6b00479. Epub 2016 Dec 14. J Nat Prod. 2016. PMID: 27966945

6

11-Aminostrychnine and N-(Strychnine-11-yl)propionamide: Synthesis, Configuration, and Pharmacological Evaluation at Glycine Receptors.

Zlotos DP, Mohsen AMY, Mandour YM, Marzouk MA, Breitinger U, Villmann C, Breitinger HG, Sotriffer C, Jensen AA, Holzgrabe U. Zlotos DP, et al. J Nat Prod. 2019 Aug 23;82(8):2332-2336. doi: 10.1021/acs.jnatprod.9b00180. Epub 2019 Aug 6. J Nat Prod. 2019. PMID: 31385511

7

C-2-Linked Dimeric Strychnine Analogues as Bivalent Ligands Targeting Glycine Receptors.

Zlotos DP, Abdelmalek CM, Botros LS, Banoub MM, Mandour YM, Breitinger U, El Nady A, Breitinger HG, Sotriffer C, Villmann C, Jensen AA, Holzgrabe U. Zlotos DP, et al. J Nat Prod. 2021 Feb 26;84(2):382-394. doi: 10.1021/acs.jnatprod.0c01030. Epub 2021 Feb 17. J Nat Prod. 2021. PMID: 33596384

8

Strychnine and its mono- and dimeric analogues: a pharmaco-chemical perspective.

Zlotos DP, Mandour YM, Jensen AA. Zlotos DP, et al. Nat Prod Rep. 2022 Oct 19;39(10):1910-1937. doi: 10.1039/d1np00079a. Nat Prod Rep. 2022. PMID: 35380133 Review.

9

Bisquaternary dimers of strychnine and brucine. A new class of potent enhancers of antagonist binding to muscarinic M2 receptors.

Zlotos DP, Buller S, Holzgrabe U, Mohr K. Zlotos DP, et al. Bioorg Med Chem. 2003 Jun 12;11(12):2627-34. doi: 10.1016/s0968-0896(03)00146-9. Bioorg Med Chem. 2003. PMID: 12757728

10

Synthesis and pharmacological evaluation of 1,2,3,4-tetrahydropyrazino[1,2-a]indole and 2-[(phenylmethylamino)methyl]-1H-indole analogues as novel melatoninergic ligands.

Markl C, Attia MI, Julius J, Sethi S, Witt-Enderby PA, Zlotos DP. Markl C, et al. Among authors: zlotos dp. Bioorg Med Chem. 2009 Jul 1;17(13):4583-94. doi: 10.1016/j.bmc.2009.04.068. Epub 2009 May 5. Bioorg Med Chem. 2009. PMID: 19473848

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