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Mutations in neutrophil elastase causing congenital neutropenia lead to cytoplasmic protein accumulation and induction of the unfolded protein response.
Köllner I, Sodeik B, Schreek S, Heyn H, von Neuhoff N, Germeshausen M, Zeidler C, Krüger M, Schlegelberger B, Welte K, Beger C. Köllner I, et al. Among authors: von neuhoff n. Blood. 2006 Jul 15;108(2):493-500. doi: 10.1182/blood-2005-11-4689. Epub 2006 Mar 21. Blood. 2006. PMID: 16551967 Free article.
High-affinity neurotrophin receptors and ligands promote leukemogenesis.
Li Z, Beutel G, Rhein M, Meyer J, Koenecke C, Neumann T, Yang M, Krauter J, von Neuhoff N, Heuser M, Diedrich H, Göhring G, Wilkens L, Schlegelberger B, Ganser A, Baum C. Li Z, et al. Among authors: von neuhoff n. Blood. 2009 Feb 26;113(9):2028-37. doi: 10.1182/blood-2008-05-155200. Epub 2008 Dec 4. Blood. 2009. PMID: 19059881 Free PMC article.
Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.
Modlich U, Kustikova OS, Schmidt M, Rudolph C, Meyer J, Li Z, Kamino K, von Neuhoff N, Schlegelberger B, Kuehlcke K, Bunting KD, Schmidt S, Deichmann A, von Kalle C, Fehse B, Baum C. Modlich U, et al. Among authors: von neuhoff n, von kalle c. Blood. 2005 Jun 1;105(11):4235-46. doi: 10.1182/blood-2004-11-4535. Epub 2005 Feb 15. Blood. 2005. PMID: 15713797 Free article.
Two cancer-predisposing variants in one family: Incidental finding of a fumarate hydrogenase (FH) germline variant in a family with Li-Fraumeni syndrome.
Pahl L, Beier R, von Neuhoff N, Auber B, Höfs M, Prott EC, Schlegelberger B, Reinhardt D, Steinemann D. Pahl L, et al. Among authors: von neuhoff n. Pediatr Blood Cancer. 2018 Oct;65(10):e27254. doi: 10.1002/pbc.27254. Epub 2018 Jun 12. Pediatr Blood Cancer. 2018. PMID: 29893455 No abstract available.
Tumor cells escape suicide gene therapy by genetic and epigenetic instability.
Frank O, Rudolph C, Heberlein C, von Neuhoff N, Schröck E, Schambach A, Schlegelberger B, Fehse B, Ostertag W, Stocking C, Baum C. Frank O, et al. Among authors: von neuhoff n. Blood. 2004 Dec 1;104(12):3543-9. doi: 10.1182/blood-2004-03-0852. Epub 2004 Aug 12. Blood. 2004. PMID: 15308565 Free article.
Familial thrombocytosis caused by the novel germ-line mutation p.Pro106Leu in the MPL gene.
El-Harith el-HA, Roesl C, Ballmaier M, Germeshausen M, Frye-Boukhriss H, von Neuhoff N, Becker C, Nürnberg G, Nürnberg P, Ahmed MA, Hübener J, Schmidtke J, Welte K, Stuhrmann M. El-Harith el-HA, et al. Among authors: von neuhoff n. Br J Haematol. 2009 Jan;144(2):185-94. doi: 10.1111/j.1365-2141.2008.07430.x. Epub 2008 Nov 19. Br J Haematol. 2009. PMID: 19036112 Free article.
Granulocyte colony-stimulating factor (G-CSF) treatment of childhood acute myeloid leukemias that overexpress the differentiation-defective G-CSF receptor isoform IV is associated with a higher incidence of relapse.
Ehlers S, Herbst C, Zimmermann M, Scharn N, Germeshausen M, von Neuhoff N, Zwaan CM, Reinhardt K, Hollink IH, Klusmann JH, Lehrnbecher T, Roettgers S, Stary J, Dworzak M, Welte K, Creutzig U, Reinhardt D. Ehlers S, et al. Among authors: von neuhoff n. J Clin Oncol. 2010 May 20;28(15):2591-7. doi: 10.1200/JCO.2009.25.9010. Epub 2010 Apr 20. J Clin Oncol. 2010. PMID: 20406937 Clinical Trial.
87 results