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Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs.
Loo L, Waller MA, Moreno CL, Cole AJ, Stella AO, Pop OT, Jochum AK, Ali OH, Denes CE, Hamoudi Z, Chung F, Aggarwal A, Low JKK, Patel K, Siddiquee R, Kang T, Mathivanan S, Mackay JP, Jochum W, Flatz L, Hesselson D, Turville S, Neely GG. Loo L, et al. Among authors: flatz l. PLoS Biol. 2023 Feb 9;21(2):e3001967. doi: 10.1371/journal.pbio.3001967. eCollection 2023 Feb. PLoS Biol. 2023. PMID: 36757924 Free PMC article.
Impaired antibody response causes persistence of prototypic T cell-contained virus.
Bergthaler A, Flatz L, Verschoor A, Hegazy AN, Holdener M, Fink K, Eschli B, Merkler D, Sommerstein R, Horvath E, Fernandez M, Fitsche A, Senn BM, Verbeek JS, Odermatt B, Siegrist CA, Pinschewer DD. Bergthaler A, et al. Among authors: flatz l. PLoS Biol. 2009 Apr 7;7(4):e1000080. doi: 10.1371/journal.pbio.1000080. PLoS Biol. 2009. PMID: 19355789 Free PMC article.
Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity.
Flatz L, Hegazy AN, Bergthaler A, Verschoor A, Claus C, Fernandez M, Gattinoni L, Johnson S, Kreppel F, Kochanek S, Broek Mv, Radbruch A, Lévy F, Lambert PH, Siegrist CA, Restifo NP, Löhning M, Ochsenbein AF, Nabel GJ, Pinschewer DD. Flatz L, et al. Nat Med. 2010 Mar;16(3):339-45. doi: 10.1038/nm.2104. Epub 2010 Feb 7. Nat Med. 2010. PMID: 20139992 Free PMC article.
T cell-dependence of Lassa fever pathogenesis.
Flatz L, Rieger T, Merkler D, Bergthaler A, Regen T, Schedensack M, Bestmann L, Verschoor A, Kreutzfeldt M, Brück W, Hanisch UK, Günther S, Pinschewer DD. Flatz L, et al. PLoS Pathog. 2010 Mar 26;6(3):e1000836. doi: 10.1371/journal.ppat.1000836. PLoS Pathog. 2010. PMID: 20360949 Free PMC article.
131 results