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Page 1
R5 and X4 HIV envelopes induce distinct gene expression profiles in primary peripheral blood mononuclear cells.
Cicala C, Arthos J, Martinelli E, Censoplano N, Cruz CC, Chung E, Selig SM, Van Ryk D, Yang J, Jagannatha S, Chun TW, Ren P, Lempicki RA, Fauci AS. Cicala C, et al. Among authors: martinelli e. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3746-51. doi: 10.1073/pnas.0511237103. Epub 2006 Feb 27. Proc Natl Acad Sci U S A. 2006. PMID: 16505369 Free PMC article.
HIV-1 gp120 induces NFAT nuclear translocation in resting CD4+ T-cells.
Cicala C, Arthos J, Censoplano N, Cruz C, Chung E, Martinelli E, Lempicki RA, Natarajan V, VanRyk D, Daucher M, Fauci AS. Cicala C, et al. Among authors: martinelli e. Virology. 2006 Feb 5;345(1):105-14. doi: 10.1016/j.virol.2005.09.052. Epub 2005 Nov 2. Virology. 2006. PMID: 16260021 Free article.
HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
Arthos J, Cicala C, Martinelli E, Macleod K, Van Ryk D, Wei D, Xiao Z, Veenstra TD, Conrad TP, Lempicki RA, McLaughlin S, Pascuccio M, Gopaul R, McNally J, Cruz CC, Censoplano N, Chung E, Reitano KN, Kottilil S, Goode DJ, Fauci AS. Arthos J, et al. Among authors: martinelli e. Nat Immunol. 2008 Mar;9(3):301-9. doi: 10.1038/ni1566. Epub 2008 Feb 10. Nat Immunol. 2008. PMID: 18264102
The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.
Cicala C, Martinelli E, McNally JP, Goode DJ, Gopaul R, Hiatt J, Jelicic K, Kottilil S, Macleod K, O'Shea A, Patel N, Van Ryk D, Wei D, Pascuccio M, Yi L, McKinnon L, Izulla P, Kimani J, Kaul R, Fauci AS, Arthos J. Cicala C, et al. Among authors: martinelli e. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20877-82. doi: 10.1073/pnas.0911796106. Epub 2009 Nov 20. Proc Natl Acad Sci U S A. 2009. PMID: 19933330 Free PMC article.
A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α4β7 and Fails to Prevent Mucosal Transmission of SHIV-SF162P3.
Arrode-Brusés G, Goode D, Kleinbeck K, Wilk J, Frank I, Byrareddy S, Arthos J, Grasperge B, Blanchard J, Zydowsky T, Gettie A, Martinelli E. Arrode-Brusés G, et al. Among authors: martinelli e. PLoS Pathog. 2016 Jun 27;12(6):e1005720. doi: 10.1371/journal.ppat.1005720. eCollection 2016 Jun. PLoS Pathog. 2016. PMID: 27348748 Free PMC article.
Integrin α4β7 Blockade Preferentially Impacts CCR6+ Lymphocyte Subsets in Blood and Mucosal Tissues of Naive Rhesus Macaques.
Calenda G, Keawvichit R, Arrode-Brusés G, Pattanapanyasat K, Frank I, Byrareddy SN, Arthos J, Cicala C, Grasperge B, Blanchard JL, Gettie A, Reimann KA, Ansari AA, Martinelli E. Calenda G, et al. Among authors: martinelli e. J Immunol. 2018 Jan 15;200(2):810-820. doi: 10.4049/jimmunol.1701150. Epub 2017 Dec 1. J Immunol. 2018. PMID: 29196458 Free PMC article.
591 results