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Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation.
Nat Med. 2006 Feb;12(2):235-9. doi: 10.1038/nm1351. Epub 2006 Feb 5.
Nat Med. 2006.
PMID: 16462802
The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies.
Fiedler U, Scharpfenecker M, Koidl S, Hegen A, Grunow V, Schmidt JM, Kriz W, Thurston G, Augustin HG.
Fiedler U, et al. Among authors: grunow v.
Blood. 2004 Jun 1;103(11):4150-6. doi: 10.1182/blood-2003-10-3685. Epub 2004 Feb 19.
Blood. 2004.
PMID: 14976056
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