Smolen GA - Search Results

1

Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752.

Smolen GA, Sordella R, Muir B, Mohapatra G, Barmettler A, Archibald H, Kim WJ, Okimoto RA, Bell DW, Sgroi DC, Christensen JG, Settleman J, Haber DA. Smolen GA, et al. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2316-21. doi: 10.1073/pnas.0508776103. Epub 2006 Feb 6. Proc Natl Acad Sci U S A. 2006. PMID: 16461907 Free PMC article.

2

Identification of a DNA-binding site and transcriptional target for the EWS-WT1(+KTS) oncoprotein.

Reynolds PA, Smolen GA, Palmer RE, Sgroi D, Yajnik V, Gerald WL, Haber DA. Reynolds PA, et al. Among authors: smolen ga. Genes Dev. 2003 Sep 1;17(17):2094-107. doi: 10.1101/gad.1110703. Epub 2003 Aug 15. Genes Dev. 2003. PMID: 12923058 Free PMC article.

3

SUMO modification is required for in vivo Hox gene regulation by the Caenorhabditis elegans Polycomb group protein SOP-2.

Zhang H, Smolen GA, Palmer R, Christoforou A, van den Heuvel S, Haber DA. Zhang H, et al. Among authors: smolen ga. Nat Genet. 2004 May;36(5):507-11. doi: 10.1038/ng1336. Epub 2004 Apr 11. Nat Genet. 2004. PMID: 15107848

4

SUMO-1 modification of the Wilms' tumor suppressor WT1.

Smolen GA, Vassileva MT, Wells J, Matunis MJ, Haber DA. Smolen GA, et al. Cancer Res. 2004 Nov 1;64(21):7846-51. doi: 10.1158/0008-5472.CAN-04-1502. Cancer Res. 2004. PMID: 15520190

5

Frequent met oncogene amplification in a Brca1/Trp53 mouse model of mammary tumorigenesis.

Smolen GA, Muir B, Mohapatra G, Barmettler A, Kim WJ, Rivera MN, Haserlat SM, Okimoto RA, Kwak E, Dahiya S, Garber JE, Bell DW, Sgroi DC, Chin L, Deng CX, Haber DA. Smolen GA, et al. Cancer Res. 2006 Apr 1;66(7):3452-5. doi: 10.1158/0008-5472.CAN-05-4181. Cancer Res. 2006. PMID: 16585167

6

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon.

Overholtzer M, Zhang J, Smolen GA, Muir B, Li W, Sgroi DC, Deng CX, Brugge JS, Haber DA. Overholtzer M, et al. Among authors: smolen ga. Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12405-10. doi: 10.1073/pnas.0605579103. Epub 2006 Aug 7. Proc Natl Acad Sci U S A. 2006. PMID: 16894141 Free PMC article.

7

A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors.

Smolen GA, Schott BJ, Stewart RA, Diederichs S, Muir B, Provencher HL, Look AT, Sgroi DC, Peterson RT, Haber DA. Smolen GA, et al. Genes Dev. 2007 Sep 1;21(17):2131-6. doi: 10.1101/gad.1561507. Epub 2007 Aug 17. Genes Dev. 2007. PMID: 17704304 Free PMC article.

8

Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway.

Zhang J, Smolen GA, Haber DA. Zhang J, et al. Among authors: smolen ga. Cancer Res. 2008 Apr 15;68(8):2789-94. doi: 10.1158/0008-5472.CAN-07-6205. Cancer Res. 2008. PMID: 18413746

9

Adenosine transporter ENT4 is a direct target of EWS/WT1 translocation product and is highly expressed in desmoplastic small round cell tumor.

Li H, Smolen GA, Beers LF, Xia L, Gerald W, Wang J, Haber DA, Lee SB. Li H, et al. Among authors: smolen ga. PLoS One. 2008 Jun 4;3(6):e2353. doi: 10.1371/journal.pone.0002353. PLoS One. 2008. PMID: 18523561 Free PMC article.

10

Coexpression of Argonaute-2 enhances RNA interference toward perfect match binding sites.

Diederichs S, Jung S, Rothenberg SM, Smolen GA, Mlody BG, Haber DA. Diederichs S, et al. Among authors: smolen ga. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9284-9. doi: 10.1073/pnas.0800803105. Epub 2008 Jun 30. Proc Natl Acad Sci U S A. 2008. PMID: 18591665 Free PMC article.

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