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Extended survival of 9- and 10-gene-edited pig heart xenografts with ischemia minimization and CD154 costimulation blockade-based immunosuppression.
Chaban R, Ileka I, McGrath G, Kinoshita K, Habibabady Z, Ma M, Diaz V, Maenaka A, Calhoun A, Dufault M, Rosales I, Laguerre CM, Sanatkar SA, Burdorf L, Ayares DL, Eyestone W, Sardana P, Kuravi K, Sorrells L, Lederman S, Lucas CG, Prather RS, Wells KD, Whitworth KM, Cooper DKC, Pierson RN 3rd. Chaban R, et al. Among authors: pierson rn 3rd. J Heart Lung Transplant. 2024 Aug 7:S1053-2498(24)01777-7. doi: 10.1016/j.healun.2024.07.022. Online ahead of print. J Heart Lung Transplant. 2024. PMID: 39097214
Research opportunities and ethical considerations for heart and lung xenotransplantation research: A report from the National Heart, Lung, and Blood Institute workshop.
Khush KK, Bernat JL, Pierson RN 3rd, Silverman HJ, Parent B, Glazier AK, Adams AB, Fishman JA, Gusmano M, Hawthorne WJ, Homan ME, Hurst DJ, Latham S, Park CG, Maschke KJ, Mohiuddin MM, Montgomery RA, Odim J, Pentz RD, Reichart B, Savulescu J, Wolpe PR, Wong RP, Fenton KN. Khush KK, et al. Among authors: pierson rn 3rd. Am J Transplant. 2024 Jun;24(6):918-927. doi: 10.1016/j.ajt.2024.03.015. Epub 2024 Mar 19. Am J Transplant. 2024. PMID: 38514013
Next Steps for Clinical Xenotransplantation in the United States.
Schiff T, Parent B, Dittmer I, Hawthorne WJ, Kwon I, Mohiuddin MM, Park CG, Stock P, Pierson RN 3rd. Schiff T, et al. Among authors: pierson rn 3rd. Ann Intern Med. 2023 Nov;176(11):1538-1539. doi: 10.7326/M23-1823. Epub 2023 Oct 31. Ann Intern Med. 2023. PMID: 37903363 No abstract available.
Antibody-mediated rejection in xenotransplantation: Can it be prevented or reversed?
Habibabady Z, McGrath G, Kinoshita K, Maenaka A, Ikechukwu I, Elias GF, Zaletel T, Rosales I, Hara H, Pierson RN 3rd, Cooper DKC. Habibabady Z, et al. Among authors: pierson rn 3rd. Xenotransplantation. 2023 Jul-Aug;30(4):e12816. doi: 10.1111/xen.12816. Epub 2023 Aug 7. Xenotransplantation. 2023. PMID: 37548030 Free PMC article. Review.
Increased human complement pathway regulatory protein gene dose is associated with increased endothelial expression and prolonged survival during ex-vivo perfusion of GTKO pig lungs with human blood.
Chaban R, McGrath G, Habibabady Z, Rosales I, Burdorf L, Ayares DL, Rybak E, Zhang T, Harris DG, Dahi S, Ali F, Parsell DM, Braileanu G, Cheng X, Sievert E, Phelps C, Azimzadeh AM, Pierson RN 3rd. Chaban R, et al. Among authors: pierson rn 3rd. Xenotransplantation. 2023 Jul-Aug;30(4):e12812. doi: 10.1111/xen.12812. Epub 2023 Jul 28. Xenotransplantation. 2023. PMID: 37504492
TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate cardiac allograft survival.
Miura S, Habibabady ZA, Pollok F, Ma M, Rosales IA, Kinoshita K, Pratts S, McGrath G, Chaban R, Fogarty S, Meibohm B, Daugherty B, Lederman S, Pierson RN 3rd. Miura S, et al. Among authors: pierson rn 3rd. Am J Transplant. 2023 Aug;23(8):1182-1193. doi: 10.1016/j.ajt.2023.03.025. Epub 2023 Apr 7. Am J Transplant. 2023. PMID: 37030662 Free PMC article.
Milestones on the path to clinical pig organ xenotransplantation.
Cooper DKC, Pierson RN 3rd. Cooper DKC, et al. Among authors: pierson rn 3rd. Am J Transplant. 2023 Mar;23(3):326-335. doi: 10.1016/j.ajt.2022.12.023. Epub 2023 Jan 18. Am J Transplant. 2023. PMID: 36775767 Free PMC article. Review.
171 results