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MET kinase inhibitor SGX523 synergizes with epidermal growth factor receptor inhibitor erlotinib in a hepatocyte growth factor-dependent fashion to suppress carcinoma growth.
Zhang YW, Staal B, Essenburg C, Su Y, Kang L, West R, Kaufman D, Dekoning T, Eagleson B, Buchanan SG, Vande Woude GF. Zhang YW, et al. Among authors: vande woude gf. Cancer Res. 2010 Sep 1;70(17):6880-90. doi: 10.1158/0008-5472.CAN-10-0898. Epub 2010 Jul 19. Cancer Res. 2010. PMID: 20643778
Phase II trial to evaluate gemcitabine and etoposide for locally advanced or metastatic pancreatic cancer.
Melnik MK, Webb CP, Richardson PJ, Luttenton CR, Campbell AD, Monroe TJ, O'Rourke TJ, Yost KJ, Szczepanek CM, Bassett MR, Truszkowski KJ, Stein P, Van Brocklin MW, Davis AT, Bedolla G, Vande Woude GF, Koo HM. Melnik MK, et al. Among authors: vande woude gf. Mol Cancer Ther. 2010 Aug;9(8):2423-9. doi: 10.1158/1535-7163.MCT-09-0854. Epub 2010 Aug 3. Mol Cancer Ther. 2010. PMID: 20682649 Clinical Trial.
Suppression of met expression: a possible cancer treatment. Commentary re: S. J. Kim et al., reduced c-Met expression by an adenovirus expressing a c-Met ribozyme inhibits tumorigenic growth and lymph node metastases of PC3-LN4 prostate tumor cells in an orthotopic nude mouse model. Clin. Cancer Res., 14: 5161-5170, 2003.
Shinomiya N, Vande Woude GF. Shinomiya N, et al. Among authors: vande woude gf. Clin Cancer Res. 2003 Nov 1;9(14):5085-90. Clin Cancer Res. 2003. PMID: 14613985 No abstract available.
294 results