Ovaa H - Search Results

1

A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib.

Chauhan D, Catley L, Li G, Podar K, Hideshima T, Velankar M, Mitsiades C, Mitsiades N, Yasui H, Letai A, Ovaa H, Berkers C, Nicholson B, Chao TH, Neuteboom ST, Richardson P, Palladino MA, Anderson KC. Chauhan D, et al. Among authors: ovaa h. Cancer Cell. 2005 Nov;8(5):407-19. doi: 10.1016/j.ccr.2005.10.013. Cancer Cell. 2005. PMID: 16286248 Free article.

2

Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib.

Berkers CR, Verdoes M, Lichtman E, Fiebiger E, Kessler BM, Anderson KC, Ploegh HL, Ovaa H, Galardy PJ. Berkers CR, et al. Among authors: ovaa h. Nat Methods. 2005 May;2(5):357-62. doi: 10.1038/nmeth759. Epub 2005 Apr 21. Nat Methods. 2005. PMID: 15846363

3

Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials.

Potts BC, Albitar MX, Anderson KC, Baritaki S, Berkers C, Bonavida B, Chandra J, Chauhan D, Cusack JC Jr, Fenical W, Ghobrial IM, Groll M, Jensen PR, Lam KS, Lloyd GK, McBride W, McConkey DJ, Miller CP, Neuteboom ST, Oki Y, Ovaa H, Pajonk F, Richardson PG, Roccaro AM, Sloss CM, Spear MA, Valashi E, Younes A, Palladino MA. Potts BC, et al. Among authors: ovaa h. Curr Cancer Drug Targets. 2011 Mar;11(3):254-84. doi: 10.2174/156800911794519716. Curr Cancer Drug Targets. 2011. PMID: 21247382 Free PMC article. Review.

4

Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132.

Crawford LJ, Walker B, Ovaa H, Chauhan D, Anderson KC, Morris TC, Irvine AE. Crawford LJ, et al. Among authors: ovaa h. Cancer Res. 2006 Jun 15;66(12):6379-86. doi: 10.1158/0008-5472.CAN-06-0605. Cancer Res. 2006. PMID: 16778216

5

Drug discovery and assay development in the ubiquitin-proteasome system.

Berkers CR, Ovaa H. Berkers CR, et al. Among authors: ovaa h. Biochem Soc Trans. 2010 Feb;38(Pt 1):14-20. doi: 10.1042/BST0380014. Biochem Soc Trans. 2010. PMID: 20074028

6

Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome.

Groll M, Berkers CR, Ploegh HL, Ovaa H. Groll M, et al. Among authors: ovaa h. Structure. 2006 Mar;14(3):451-6. doi: 10.1016/j.str.2005.11.019. Structure. 2006. PMID: 16531229 Free article.

7

Fluorescence-based proteasome activity profiling.

de Jong A, Schuurman KG, Rodenko B, Ovaa H, Berkers CR. de Jong A, et al. Among authors: ovaa h. Methods Mol Biol. 2012;803:183-204. doi: 10.1007/978-1-61779-364-6_13. Methods Mol Biol. 2012. PMID: 22065226

8

Probing the specificity and activity profiles of the proteasome inhibitors bortezomib and delanzomib.

Berkers CR, Leestemaker Y, Schuurman KG, Ruggeri B, Jones-Bolin S, Williams M, Ovaa H. Berkers CR, et al. Among authors: ovaa h. Mol Pharm. 2012 May 7;9(5):1126-35. doi: 10.1021/mp2004143. Epub 2012 Apr 16. Mol Pharm. 2012. PMID: 22432738

9

Immunotherapeutic potential for ceramide-based activators of iNKT cells.

Berkers CR, Ovaa H. Berkers CR, et al. Among authors: ovaa h. Trends Pharmacol Sci. 2005 May;26(5):252-7. doi: 10.1016/j.tips.2005.03.005. Trends Pharmacol Sci. 2005. PMID: 15860372 Review.

10

Profiling proteasome activity in tissue with fluorescent probes.

Berkers CR, van Leeuwen FW, Groothuis TA, Peperzak V, van Tilburg EW, Borst J, Neefjes JJ, Ovaa H. Berkers CR, et al. Among authors: ovaa h. Mol Pharm. 2007 Sep-Oct;4(5):739-48. doi: 10.1021/mp0700256. Epub 2007 Aug 21. Mol Pharm. 2007. PMID: 17708652

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