Borza DB - Search Results

1

Distinct epitopes for anti-glomerular basement membrane alport alloantibodies and goodpasture autoantibodies within the noncollagenous domain of alpha3(IV) collagen: a janus-faced antigen.

Wang XP, Fogo AB, Colon S, Giannico G, Abul-Ezz SR, Miner JH, Borza DB. Wang XP, et al. Among authors: borza db. J Am Soc Nephrol. 2005 Dec;16(12):3563-71. doi: 10.1681/ASN.2005060670. Epub 2005 Oct 19. J Am Soc Nephrol. 2005. PMID: 16236801

2

Quaternary organization of the goodpasture autoantigen, the alpha 3(IV) collagen chain. Sequestration of two cryptic autoepitopes by intrapromoter interactions with the alpha4 and alpha5 NC1 domains.

Borza DB, Bondar O, Todd P, Sundaramoorthy M, Sado Y, Ninomiya Y, Hudson BG. Borza DB, et al. J Biol Chem. 2002 Oct 18;277(42):40075-83. doi: 10.1074/jbc.M207769200. Epub 2002 Aug 21. J Biol Chem. 2002. PMID: 12193605 Free article.

3

Pathogenesis of Goodpasture syndrome: a molecular perspective.

Borza DB, Neilson EG, Hudson BG. Borza DB, et al. Semin Nephrol. 2003 Nov;23(6):522-31. doi: 10.1053/s0270-9295(03)00131-1. Semin Nephrol. 2003. PMID: 14631560 Review.

4

Recurrent Goodpasture's disease secondary to a monoclonal IgA1-kappa antibody autoreactive with the alpha1/alpha2 chains of type IV collagen.

Borza DB, Chedid MF, Colon S, Lager DJ, Leung N, Fervenza FC. Borza DB, et al. Am J Kidney Dis. 2005 Feb;45(2):397-406. doi: 10.1053/j.ajkd.2004.09.029. Am J Kidney Dis. 2005. PMID: 15685519

5

Goodpasture autoantibodies unmask cryptic epitopes by selectively dissociating autoantigen complexes lacking structural reinforcement: novel mechanisms for immune privilege and autoimmune pathogenesis.

Borza DB, Bondar O, Colon S, Todd P, Sado Y, Neilson EG, Hudson BG. Borza DB, et al. J Biol Chem. 2005 Jul 22;280(29):27147-54. doi: 10.1074/jbc.M504050200. Epub 2005 May 24. J Biol Chem. 2005. PMID: 15917228 Free article.

6

Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3.

Borza CM, Pozzi A, Borza DB, Pedchenko V, Hellmark T, Hudson BG, Zent R. Borza CM, et al. Among authors: borza db. J Biol Chem. 2006 Jul 28;281(30):20932-20939. doi: 10.1074/jbc.M601147200. Epub 2006 May 26. J Biol Chem. 2006. PMID: 16731529 Free article.

7

Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice.

Kang JS, Wang XP, Miner JH, Morello R, Sado Y, Abrahamson DR, Borza DB. Kang JS, et al. Among authors: borza db. J Am Soc Nephrol. 2006 Jul;17(7):1962-9. doi: 10.1681/ASN.2006020165. Epub 2006 Jun 12. J Am Soc Nephrol. 2006. PMID: 16769745

8

The alloantigenic sites of alpha3alpha4alpha5(IV) collagen: pathogenic X-linked alport alloantibodies target two accessible conformational epitopes in the alpha5NC1 domain.

Kang JS, Kashtan CE, Turner AN, Heidet L, Hudson BG, Borza DB. Kang JS, et al. Among authors: borza db. J Biol Chem. 2007 Apr 6;282(14):10670-7. doi: 10.1074/jbc.M611892200. Epub 2007 Feb 9. J Biol Chem. 2007. PMID: 17293596 Free article.

9

Autoepitopes and alloepitopes of type IV collagen: role in the molecular pathogenesis of anti-GBM antibody glomerulonephritis.

Borza DB. Borza DB. Nephron Exp Nephrol. 2007;106(2):e37-43. doi: 10.1159/000101791. Epub 2007 Jun 6. Nephron Exp Nephrol. 2007. PMID: 17570938 Review.

10

Human podocytes adhere to the KRGDS motif of the alpha3alpha4alpha5 collagen IV network.

Borza CM, Borza DB, Pedchenko V, Saleem MA, Mathieson PW, Sado Y, Hudson HM, Pozzi A, Saus J, Abrahamson DR, Zent R, Hudson BG. Borza CM, et al. Among authors: borza db. J Am Soc Nephrol. 2008 Apr;19(4):677-84. doi: 10.1681/ASN.2007070793. Epub 2008 Jan 30. J Am Soc Nephrol. 2008. PMID: 18235087 Free PMC article.

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