Weinstein H - Search Results

1

The structure and dynamics of GPCR oligomers: a new focus in models of cell-signaling mechanisms and drug design.

Filizola M, Weinstein H. Filizola M, et al. Among authors: weinstein h. Curr Opin Drug Discov Devel. 2005 Sep;8(5):577-84. Curr Opin Drug Discov Devel. 2005. PMID: 16159019 Review.

2

Prediction of heterodimerization interfaces of G-protein coupled receptors with a new subtractive correlated mutation method.

Filizola M, Olmea O, Weinstein H. Filizola M, et al. Among authors: weinstein h. Protein Eng. 2002 Nov;15(11):881-5. doi: 10.1093/protein/15.11.881. Protein Eng. 2002. PMID: 12538907

3

Structural models for dimerization of G-protein coupled receptors: the opioid receptor homodimers.

Filizola M, Weinstein H. Filizola M, et al. Among authors: weinstein h. Biopolymers. 2002;66(5):317-25. doi: 10.1002/bip.10311. Biopolymers. 2002. PMID: 12539260

4

Mechanistic insights from a refined three-dimensional model of integrin alphaIIbbeta3.

Filizola M, Hassan SA, Artoni A, Coller BS, Weinstein H. Filizola M, et al. Among authors: weinstein h. J Biol Chem. 2004 Jun 4;279(23):24624-30. doi: 10.1074/jbc.M400243200. Epub 2004 Mar 30. J Biol Chem. 2004. PMID: 15056669 Free article.

5

The study of G-protein coupled receptor oligomerization with computational modeling and bioinformatics.

Filizola M, Weinstein H. Filizola M, et al. Among authors: weinstein h. FEBS J. 2005 Jun;272(12):2926-38. doi: 10.1111/j.1742-4658.2005.04730.x. FEBS J. 2005. PMID: 15955053 Free article. Review.

6

Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation.

Guo W, Shi L, Filizola M, Weinstein H, Javitch JA. Guo W, et al. Among authors: weinstein h. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17495-500. doi: 10.1073/pnas.0508950102. Epub 2005 Nov 21. Proc Natl Acad Sci U S A. 2005. PMID: 16301531 Free PMC article.

7

Hallucinogen actions on 5-HT receptors reveal distinct mechanisms of activation and signaling by G protein-coupled receptors.

Weinstein H. Weinstein H. AAPS J. 2006 Jan 6;7(4):E871-84. doi: 10.1208/aapsj070485. AAPS J. 2006. PMID: 16594640 Free PMC article. Review.

8

Dynamic models of G-protein coupled receptor dimers: indications of asymmetry in the rhodopsin dimer from molecular dynamics simulations in a POPC bilayer.

Filizola M, Wang SX, Weinstein H. Filizola M, et al. Among authors: weinstein h. J Comput Aided Mol Des. 2006 Jul-Aug;20(7-8):405-16. doi: 10.1007/s10822-006-9053-3. Epub 2006 Nov 7. J Comput Aided Mol Des. 2006. PMID: 17089205 Free PMC article.

9

Modeling activated states of GPCRs: the rhodopsin template.

Niv MY, Skrabanek L, Filizola M, Weinstein H. Niv MY, et al. Among authors: weinstein h. J Comput Aided Mol Des. 2006 Jul-Aug;20(7-8):437-48. doi: 10.1007/s10822-006-9061-3. Epub 2006 Nov 11. J Comput Aided Mol Des. 2006. PMID: 17103019 Free PMC article.

10

Mutations affecting the oligomerization interface of G-protein-coupled receptors revealed by a novel de novo protein design framework.

Taylor MS, Fung HK, Rajgaria R, Filizola M, Weinstein H, Floudas CA. Taylor MS, et al. Among authors: weinstein h. Biophys J. 2008 Apr 1;94(7):2470-81. doi: 10.1529/biophysj.107.117622. Epub 2008 Jan 4. Biophys J. 2008. PMID: 18178645 Free PMC article.

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