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Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain.
Heidel F, Solem FK, Breitenbuecher F, Lipka DB, Kasper S, Thiede MH, Brandts C, Serve H, Roesel J, Giles F, Feldman E, Ehninger G, Schiller GJ, Nimer S, Stone RM, Wang Y, Kindler T, Cohen PS, Huber C, Fischer T. Heidel F, et al. Among authors: brandts c. Blood. 2006 Jan 1;107(1):293-300. doi: 10.1182/blood-2005-06-2469. Epub 2005 Sep 8. Blood. 2006. PMID: 16150941 Free article.
High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets.
Müller-Tidow C, Schwäble J, Steffen B, Tidow N, Brandt B, Becker K, Schulze-Bahr E, Halfter H, Vogt U, Metzger R, Schneider PM, Büchner T, Brandts C, Berdel WE, Serve H. Müller-Tidow C, et al. Among authors: brandts c. Clin Cancer Res. 2004 Feb 15;10(4):1241-9. doi: 10.1158/1078-0432.ccr-0954-03. Clin Cancer Res. 2004. PMID: 14977821
Growth inhibition and induction of apoptosis in acute myeloid leukemia cells by new indolinone derivatives targeting fibroblast growth factor, platelet-derived growth factor, and vascular endothelial growth factor receptors.
Kulimova E, Oelmann E, Bisping G, Kienast J, Mesters RM, Schwäble J, Hilberg F, Roth GJ, Munzert G, Stefanic M, Steffen B, Brandts C, Müller-Tidow C, Kolkmeyer A, Büchner T, Serve H, Berdel WE. Kulimova E, et al. Among authors: brandts c. Mol Cancer Ther. 2006 Dec;5(12):3105-12. doi: 10.1158/1535-7163.MCT-06-0323. Mol Cancer Ther. 2006. PMID: 17172413
Oncogenic signaling in acute myeloid leukemia.
Brandts CH, Berdel WE, Serve H. Brandts CH, et al. Curr Drug Targets. 2007 Feb;8(2):237-46. doi: 10.2174/138945007779940197. Curr Drug Targets. 2007. PMID: 17305501 Review.
122 results