Mounier CM - Search Results

1

Inhibition of secretory phospholipase A2. 1-design, synthesis and structure-activity relationship studies starting from 4-tetradecyloxybenzamidine to obtain specific inhibitors of group II sPLA2s.

Assogba L, Ahamada-Himidi A, Habich NM, Aoun D, Boukli L, Massicot F, Mounier CM, Huet J, Lamouri A, Ombetta JE, Godfroid JJ, Dong CZ, Heymans F. Assogba L, et al. Among authors: mounier cm. Eur J Med Chem. 2005 Sep;40(9):850-61. doi: 10.1016/j.ejmech.2005.03.027. Eur J Med Chem. 2005. PMID: 16084626

2

Total direct chemical synthesis and biological activities of human group IIA secretory phospholipase A2.

Dong CZ, Romieu A, Mounier CM, Heymans F, Roques BP, Godfroid JJ. Dong CZ, et al. Among authors: mounier cm. Biochem J. 2002 Jul 15;365(Pt 2):505-11. doi: 10.1042/BJ20011648. Biochem J. 2002. PMID: 11936952 Free PMC article.

3

Structure-activity relationships in platelet-activating factor (PAF). 11-From PAF-antagonism to phospholipase A(2) inhibition: syntheses and structure-activity relationships in 1-arylsulfamido-2-alkylpiperazines.

Binisti C, Assogba L, Touboul E, Mounier C, Huet J, Ombetta JE, Dong CZ, Redeuilh C, Heymans F, Godfroid JJ. Binisti C, et al. Eur J Med Chem. 2001 Oct;36(10):809-28. doi: 10.1016/s0223-5234(01)01274-0. Eur J Med Chem. 2001. PMID: 11738488

4

4-Alkoxybenzamidines as new potent phospholipase A2 inhibitors.

Aitdafoun M, Mounier C, Heymans F, Binisti C, Bon C, Godfroid JJ. Aitdafoun M, et al. Biochem Pharmacol. 1996 Mar 22;51(6):737-42. doi: 10.1016/0006-2952(95)02172-8. Biochem Pharmacol. 1996. PMID: 8602868

5

Structure-activity relationships in platelet activating factor. 9. From PAF-antagonism to PLA2 inhibition.

Binisti C, Touboul E, Mounier C, Heymans F, Bon C, Godfroid JJ. Binisti C, et al. J Lipid Mediat Cell Signal. 1997 Jan;15(2):125-44. doi: 10.1016/s0929-7855(96)00453-1. J Lipid Mediat Cell Signal. 1997. PMID: 9034960

6

A new phospholipase A2 inhibitor, unrelated to substrate analogues: kinetic characterization of the inhibition of secretory phospholipases A2 by PMS 832.

Binisti C, Mounier C, Touboul E, Heymans F, Bon C, Godfroid JJ. Binisti C, et al. J Lipid Mediat Cell Signal. 1997 Jul;16(3):171-87. doi: 10.1016/s0929-7855(97)00008-4. J Lipid Mediat Cell Signal. 1997. PMID: 9246606

7

Inhibition of prothrombinase by human secretory phospholipase A2 involves binding to factor Xa.

Mounier CM, Hackeng TM, Schaeffer F, Faure G, Bon C, Griffin JH. Mounier CM, et al. J Biol Chem. 1998 Sep 11;273(37):23764-72. doi: 10.1074/jbc.273.37.23764. J Biol Chem. 1998. PMID: 9726985 Free article.

8

The anticoagulant effect of the human secretory phospholipase A2 on blood plasma and on a cell-free system is due to a phospholipid-independent mechanism of action involving the inhibition of factor Va.

Mounier C, Franken PA, Verheij HM, Bon C. Mounier C, et al. Eur J Biochem. 1996 May 1;237(3):778-85. doi: 10.1111/j.1432-1033.1996.0778p.x. Eur J Biochem. 1996. PMID: 8647125 Free article.

9

Platelet secretory phospholipase A2 fails to induce rabbit platelet activation and to release arachidonic acid in contrast with venom phospholipases A2.

Mounier C, Vargaftig BB, Franken PA, Verheij HM, Bon C, Touqui L. Mounier C, et al. Biochim Biophys Acta. 1994 Aug 25;1214(1):88-96. doi: 10.1016/0005-2760(94)90013-2. Biochim Biophys Acta. 1994. PMID: 8068732

10

Basic residues of human group IIA phospholipase A2 are important for binding to factor Xa and prothrombinase inhibition comparison with other mammalian secreted phospholipases A2.

Mounier CM, Luchetta P, Lecut C, Koduri RS, Faure G, Lambeau G, Valentin E, Singer A, Ghomashchi F, Béguin S, Gelb MH, Bon C. Mounier CM, et al. Eur J Biochem. 2000 Aug;267(16):4960-9. doi: 10.1046/j.1432-1327.2000.01523.x. Eur J Biochem. 2000. PMID: 10931177 Free article.

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