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Inhibition of secretory phospholipase A2. 1-design, synthesis and structure-activity relationship studies starting from 4-tetradecyloxybenzamidine to obtain specific inhibitors of group II sPLA2s.
Assogba L, Ahamada-Himidi A, Habich NM, Aoun D, Boukli L, Massicot F, Mounier CM, Huet J, Lamouri A, Ombetta JE, Godfroid JJ, Dong CZ, Heymans F. Assogba L, et al. Among authors: ahamada himidi a. Eur J Med Chem. 2005 Sep;40(9):850-61. doi: 10.1016/j.ejmech.2005.03.027. Eur J Med Chem. 2005. PMID: 16084626
Inhibition of secretory phospholipase A2. 2-Synthesis and structure-activity relationship studies of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one (PMS1062) derivatives specific for group II enzyme.
Dong CZ, Ahamada-Himidi A, Plocki S, Aoun D, Touaibia M, Meddad-Bel Habich N, Huet J, Redeuilh C, Ombetta JE, Godfroid JJ, Massicot F, Heymans F. Dong CZ, et al. Among authors: ahamada himidi a. Bioorg Med Chem. 2005 Mar 15;13(6):1989-2007. doi: 10.1016/j.bmc.2005.01.016. Bioorg Med Chem. 2005. PMID: 15727853